DR Parmar, JY Soni, R Guduru, RH Rayani… - Bioorganic …, 2021 - Elsevier
With the aim to discover potent and novel antitumor agents, a series of thiourea compounds bearing 3-(4-methoxyphenyl) azetidine moiety were designed according to the essential …
M Catarro, JL Serrano, SS Ramos, S Silvestre… - Bioorganic …, 2019 - Elsevier
Nimesulide is a nonsteroidal anti-inflammatory drug possessing analgesic and antipyretic properties. This drug is considered a selective cyclooxygenase-2 (COX-2) inhibitor and …
Squalene is a natural dehydrotriterpenic hydrocarbon (C30H50) with six double bonds, an intermediate for the biosynthesis of phytosterol/cholesterol in plants/animals and humans …
A Bielenica, S Beegum, YS Mary, YS Mary… - Journal of Molecular …, 2020 - Elsevier
This manuscript presents the computational and experimental studies of a new thiourea derivative 1-(4-chloro-3-nitrophenyl)-3-(3, 4-dichlorophenyl) thiourea (CNDCT). Scaled …
YS Mary, YS Mary, A Bielenica, S Armaković… - Journal of Molecular …, 2021 - Springer
Abstract Spectroscopic analysis of 1-(2-fluorophenyl)-3-[3-(trifluoromethyl) phenyl] thiourea (FPTT) is reported. Experimental and theoretical analyses of FPTT, with molecular dynamics …
W Liu, J Zhou, T Zhang, H Zhu, H Qian, H Zhang… - Bioorganic & medicinal …, 2012 - Elsevier
Thiourea derivatives (6a–e) were developed and screened for antitumor and anti- inflammatory activity. Most of the compounds exhibited growth inhibitory effects comparable …
A series of new thiourea derivatives of 1, 2, 4-triazole have been synthesized. The difference in structures of obtained compounds are directly connected with the kind of isothiocyanate …
In research, anticancer agents, such as thiourea derivative compounds, and metal complexes, such as those complexed with iron (III) metal, are often studied. The metal …
G Sanna, S Madeddu, G Giliberti, S Piras, M Struga… - Molecules, 2018 - mdpi.com
A series of 2-(1 H-indol-3-yl) ethylthiourea derivatives were prepared by condensation of 2- (1 H-indol-3-yl) ethanamine with appropriate aryl/alkylisothiocyanates in anhydrous media …