Emerging roles and functional mechanisms of PIWI-interacting RNAs
X Wang, A Ramat, M Simonelig, MF Liu - Nature Reviews Molecular …, 2023 - nature.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
PIWI-interacting RNAs: small RNAs with big functions
In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs
JY Kang, Z Wen, D Pan, Y Zhang, Q Li, A Zhong, X Yu… - Science, 2022 - science.org
Postmeiotic spermatids use a unique strategy to coordinate gene expression with
morphological transformation, in which transcription and translation take place at separate …
morphological transformation, in which transcription and translation take place at separate …
The emerging role of the piRNA/piwi complex in cancer
Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
One loop to rule them all: the ping-pong cycle and piRNA-guided silencing
The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects
the genetic information of animal germ cells from the deleterious effects of molecular …
the genetic information of animal germ cells from the deleterious effects of molecular …
PIWI-interacting RNA: its biogenesis and functions
YW Iwasaki, MC Siomi, H Siomi - Annual review of biochemistry, 2015 - annualreviews.org
PIWI-interacting RNAs (piRNAs) are a class of small RNAs that are 24–31 nucleotides in
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
[HTML][HTML] Variant PNLDC1, Defective piRNA Processing, and Azoospermia
L Nagirnaja, N Mørup, JE Nielsen… - … England Journal of …, 2021 - Mass Medical Soc
Background P-element–induced wimpy testis (PIWI)–interacting RNAs (piRNAs) are short
(21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ …
(21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ …
piRNAs: from biogenesis to function
EM Weick, EA Miska - Development, 2014 - journals.biologists.com
Distinguishing self from non-self plays a crucial role in safeguarding the germlines of
metazoa from mobile DNA elements. Since their discovery less than a decade ago, Piwi …
metazoa from mobile DNA elements. Since their discovery less than a decade ago, Piwi …
m6A-dependent biogenesis of circular RNAs in male germ cells
The majority of circular RNAs (circRNAs) spliced from coding genes contain open reading
frames (ORFs) and thus, have protein coding potential. However, it remains unknown what …
frames (ORFs) and thus, have protein coding potential. However, it remains unknown what …
The latest advances in the reproductive toxicity of microcystin-LR
S Zhang, X Du, H Liu, MD Losiewic, X Chen, Y Ma… - Environmental …, 2021 - Elsevier
Abstract Microcystin-LR (MC-LR) is an emerging environmental pollutant produced by
cyanobacteria that poses a threat to wild life and human health. In recent years, the …
cyanobacteria that poses a threat to wild life and human health. In recent years, the …