Schizophrenia is a complex neuropsychiatric syndrome with a heterogeneous genetic,
neurobiological, and phenotypic profile. Currently, no objective biological measures—that is …

Abstract Since Emil Kraepelin's conceptualization of endogenous psychoses as dementia
praecox and manic depression, the separation between primary psychotic disorders and …

Neurobiological abnormalities associated with psychiatric disorders do not map well to
existing diagnostic categories. High co-morbidity suggests dimensional circuit-level …

It is well known that most brain disorders are complex diseases, such as Alzheimer's
disease (AD) and schizophrenia (SCZ). In general, brain regions and their interactions can …

Antipsychotics represent the mainstay of schizophrenia pharmacological therapy, and their
role has been expanded in the last years to mood disorders treatment. Although introduced …

The alterations of connectome in schizophrenia have been reported, but the results remain
inconsistent. We conducted a systematic review and random-effects meta-analysis on …

Background: Brain connectome research based on graph theoretical analysis shows that
small-world topological properties play an important role in the structural and functional …

The pharmacological modulation of glutamatergic neurotransmission to improve cognitive
function has been a focus of intensive research, particularly in relation to the cognitive …

Diffusion tensor imaging (DTI) studies show widespread white matter abnormalities in
schizophrenia, but it is difficult to directly relate these parameters to biological processes …

Schizophrenia is a heterogeneous mental disorder with unknown etiology or pathological
characteristics. Microstate analysis of the electroencephalogram (EEG) signal has shown …