Mild cognitive impairment in Huntington's disease: challenges and outlooks
KA Jellinger - Journal of Neural Transmission, 2024 - Springer
Although Huntington's disease (HD) has classically been viewed as an autosomal-dominant
inherited neurodegenerative motor disorder, cognitive and/or behavioral changes are …
inherited neurodegenerative motor disorder, cognitive and/or behavioral changes are …
CAG repeats within the non-pathological range in the HTT gene influence personality traits in patients with subjective cognitive decline: a 13-year follow-up study
V Moschini, S Mazzeo, S Bagnoli, S Padiglioni… - Frontiers in …, 2022 - frontiersin.org
Objective: HTT is a gene containing a key region of CAG repeats. When expanded beyond
39 repeats, Huntington disease (HD) develops. HTT genes with< 35 repeats are not …
39 repeats, Huntington disease (HD) develops. HTT genes with< 35 repeats are not …
Intermediate alleles of HTT: A new pathway in longevity
A Ingannato, S Bagnoli, V Bessi, C Ferrari… - Journal of the …, 2022 - Elsevier
Centenarians are the best example of successful aging, reaching extreme longevity
escaping age-related diseases. Genome sequencing studies provided evidence for genetic …
escaping age-related diseases. Genome sequencing studies provided evidence for genetic …
Huntingtin gene intermediate alleles influence the progression from subjective cognitive decline to mild cognitive impairment: A 14‐year follow‐up study
S Mazzeo, F Emiliani, S Bagnoli… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Huntingtin (HTT) is a gene containing a key region of CAG
repeats. HTT alleles containing from 27 to 35 CAG repeats are termed intermediate alleles …
repeats. HTT alleles containing from 27 to 35 CAG repeats are termed intermediate alleles …
The Trail Making Test (part B) is associated with working memory: A concurrent validity study
JE Pérez-Parra, F Restrepo-de-Mejía - Applied Neuropsychology …, 2023 - Taylor & Francis
Abstract The Test Making Test (TMT) was originally created as a distributed attention test.
Part B (TMT-B) has been proposed as representative of executive functions as effective …
Part B (TMT-B) has been proposed as representative of executive functions as effective …
The Role of Alleles with Intermediate Numbers of Trinucleotide Repeats in Parkinson's Disease and Other Neurodegenerative Diseases
MA Nikitina, EY Bragina, MS Nazarenko… - Neuroscience and …, 2023 - Springer
Genetic factors underlie the pathological processes responsible for the manifestations of a
wide range of neurodegenerative diseases. The expansion of unstable trinucleotide repeats …
wide range of neurodegenerative diseases. The expansion of unstable trinucleotide repeats …
РОЛЬ АЛЛЕЛЕЙ С ПРОМЕЖУТОЧНЫМ КОЛИЧЕСТВОМ ТРИНУКЛЕОТИДНЫХ ПОВТОРОВ ПРИ БОЛЕЗНИ ПАРКИНСОНА И ДРУГИХ …
МА НИКИТИНА, ЕЮ БРАГИНА, МС НАЗАРЕНКО… - 2022 - elibrary.ru
Генетические факторы лежат в основе патологических процессов, являющихся
причиной манифестации широкого круга нейродегенеративных заболеваний. В …
причиной манифестации широкого круга нейродегенеративных заболеваний. В …
[引用][C] On the Metaphysical and Ethical Discourse of Reproductive and Human Germline Genome Editing Technologies: A Novel Account and Addressing the Non …
V Nagam