Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Ergothioneine (EGT) is a high-value natural sulfur-containing amino acid and has been
shown to possess extremely potent antioxidant and cytoprotective activities. At present, EGT …

To further increase the production efficiency of microbial shikimate, a valuable compound
widely used in the pharmaceutical and chemical industries, ten key target genes contributing …

Filamentous fungi are critical in the transition to a more sustainable food system. While
genetic modification of these organisms has promise for enhancing the nutritional value …

Ergothioneine (ERG) is an unusual sulfur-containing amino acid with antioxidant activity that
can be synthesized by certain bacteria and fungi. Microbial fermentation is a promising …

Ergothioneine (EGT) is a high-value natural antioxidant that cannot be synthesized by the
human body. This study showed that Rhodotorula mucilaginosa DL-X01 can use untreated …

Ergothioneine is a histidine derivative with a 2-mercaptoimidazole side chain and a
trimethylated α-amino group. Although the physiological function of this natural product is …

Kynurenic acid (KYNA) is an antioxidant degradation product of tryptophan that has been
shown to have a variety of cytoprotective, neuroprotective and neuronal signalling …

The exchange of small molecules between the cell and the environment happens through
transporter proteins. Besides nutrients and native metabolic products, xenobiotic molecules …

Yarrowia lipolytica is widely used in biotechnology to produce recombinant proteins, food
ingredients and diverse natural products. However, unstable expression of plasmids, difficult …