Purpose: Optical coherence tomography (OCT) has enabled “virtual biopsy” of the living
human retina, revolutionizing both basic retina research and clinical practice over the past …

Diabetic retinopathy and diabetic macular edema result from chronic damage to the
neurovascular structures of the retina. The pathophysiology of retinal damage remains …

Due to the increasing prevalence of diabetes mellitus, demand for diabetic retinopathy (DR)
screening platforms is steeply increasing. Early detection and treatment of DR are key public …

This is a comprehensive review of the principles and applications of adaptive optics (AO) in
ophthalmology. It has been combined with flood illumination ophthalmoscopy, scanning …

Purpose: To quantify microvasculature changes in the superficial (SCP), middle (MCP), and
deep capillary plexuses (DCP) in diabetic retinopathy (DR). Methods: Retrospective cross …

Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …

We used a confocal adaptive optics scanning laser ophthalmoscope (AOSLO) to image the
retina of subjects with non-proliferative diabetic retinopathy (NPDR). To improve …

Purpose.: Microaneurysms (MAs) are considered a hallmark of retinal vascular disease, yet
what little is known about them is mostly based upon histology, not clinical observation …

Over the last decade, there has been an expansion of imaging modalities available to
clinicians to diagnose and monitor the treatment and progression of diabetic retinopathy …

Retinal vascular diseases are a leading cause for blindness and partial sight certifications.
By applying adaptive optics (AO) to conventional imaging modalities, the microstructures of …