Cross-species insights into genomic adaptations to hypoxia
ME Pamenter, JE Hall, Y Tanabe… - Frontiers in Genetics, 2020 - frontiersin.org
Over millions of years, vertebrate species populated vast environments spanning the globe.
Among the most challenging habitats encountered were those with limited availability of …
Among the most challenging habitats encountered were those with limited availability of …
Selection signatures for high‐altitude adaptation in ruminants
J Friedrich, P Wiener - Animal Genetics, 2020 - Wiley Online Library
High‐altitude areas are important socio‐economical habitats with ruminants serving as a
major source of food and commodities for humans. Living at high altitude, however, is …
major source of food and commodities for humans. Living at high altitude, however, is …
Characterizing metabolome signature of colostrum, transition and mature milk of indigenous cows (Bos indicus) adapted to high altitude environment of Leh-Ladakh
This study has identified 46 metabolites in colostrum, transition milk and mature milk of
unique indigenous high altitude adapted Ladakhi cows using 1D 1H 800 MHz NMR …
unique indigenous high altitude adapted Ladakhi cows using 1D 1H 800 MHz NMR …
[HTML][HTML] Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects
W Wei, Q Zeng, Y Wang, X Guo, T Fan, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
Using chemoproteomic techniques, we first identified EIF2AK2, eEF1A1, PRDX3 and VPS4B
as direct targets of berberine (BBR) for its synergistically anti-inflammatory effects. Of them …
as direct targets of berberine (BBR) for its synergistically anti-inflammatory effects. Of them …
Genome-wide association analyses identify genotype-by-environment interactions of growth traits in Simmental cattle
Understanding genotype-by-environment interactions (G× E) is crucial to understand
environmental adaptation in mammals and improve the sustainability of agricultural …
environmental adaptation in mammals and improve the sustainability of agricultural …
Haplotype-resolved 3D chromatin architecture of the hybrid pig
Y Lin, J Li, Y Gu, L Jin, J Bai, J Zhang, Y Wang… - Genome …, 2024 - genome.cshlp.org
In diploid mammals, allele-specific three-dimensional (3D) genome architecture may lead to
imbalanced gene expression. Through ultradeep in situ Hi-C sequencing of three …
imbalanced gene expression. Through ultradeep in situ Hi-C sequencing of three …
Discovery of genomic characteristics and selection signatures in southern Chinese local cattle
Y Liu, L Xu, L Yang, G Zhao, J Li, D Liu, Y Li - Frontiers in Genetics, 2020 - frontiersin.org
Chinese local cattle with a high level of genetic diversity mainly originate from two
subspecies; the cattle in northern China are primarily Bos Taurus, and the cattle in southern …
subspecies; the cattle in northern China are primarily Bos Taurus, and the cattle in southern …
Genome-Wide Association Analysis Reveals Novel Loci Related with Visual Score Traits in Nellore Cattle Raised in Pasture–Based Systems
Simple Summary Genome-wide association studies attempt to understand the genetic
structure through the expression of genes that influence a given productive trait. This work …
structure through the expression of genes that influence a given productive trait. This work …
Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome
Acute high-altitude (HA) exposure can induce several pathologies. Dexamethasone (DEX)
can be taken prophylactically to prevent HA disease, but the mechanism by which it acts in …
can be taken prophylactically to prevent HA disease, but the mechanism by which it acts in …
Selection of species specific panel of reference genes in peripheral blood mononuclear cells of native livestock species adapted to trans-Himalayan region of Leh …
The identification of appropriate references genes is an integral component of any gene
expression-based study for getting accuracy and reliability in data interpretation. In this …
expression-based study for getting accuracy and reliability in data interpretation. In this …