Metabolic profiling and metabolites fingerprints in human hypertension: discovery and potential

JO Onuh, H Qiu - Metabolites, 2021 - mdpi.com
Early detection of pathogenesis through biomarkers holds the key to controlling
hypertension and preventing cardiovascular complications. Metabolomics profiling acts as a …

Identification of biomarkers for essential hypertension based on metabolomics

Y Deng, C Huang, J Su, CW Pan, C Ke - Nutrition, Metabolism and …, 2021 - Elsevier
Aim Essential hypertension (EH) is one of the most important public health problems
worldwide. However, the pathogenesis of EH is unclear and early diagnostic methods are …

Application of omics in hypertension and resistant hypertension

J Guo, X Guo, Y Sun, Z Li, P Jia - Hypertension Research, 2022 - nature.com
Hypertension is a major modifiable risk factor that affects the global health burden. Despite
the availability of multiple antihypertensive drugs, blood pressure is often not optimally …

Metabolome-wide association study of cord blood metabolites with blood pressure in childhood and adolescence

M Zhang, TM Brady, JP Buckley, LJ Appel, X Hong… - …, 2022 - Am Heart Assoc
Background: No studies have examined whether the cord blood metabolome—a reflection
of in utero metabolism—influences blood pressure (BP) in children. Objectives: To examine …

Comprehensive biomarker profiling of hypertension in 36 985 Finnish individuals

J Palmu, E Tikkanen, AS Havulinna… - Journal of …, 2022 - journals.lww.com
Objective: Previous studies on the association between metabolic biomarkers and
hypertension have been limited by small sample sizes, low number of studied biomarkers …

Metabolomics of Plasma in XLH Patients with Arterial Hypertension: New Insights into the Underlying Mechanisms

LC López-Romero, JJ Broseta… - International Journal of …, 2024 - mdpi.com
X-linked hypophosphatemia (XLH) is a rare genetic disorder that increases fibroblast growth
factor 23 (FGF23). XLH patients have an elevated risk of early-onset hypertension. The …

Identification of potential metabolic markers of hypertension in Chinese children

J Sun, M Zhao, L Yang, X Liu, L Pacifico… - International Journal …, 2021 - Wiley Online Library
Background. Studies in adults have shown that several metabolites across multiple
pathways are strongly associated with hypertension. However, as yet, to our knowledge, no …

Metabolomics study of blood pressure salt-sensitivity and hypertension

M Shi, J He, C Li, X Lu, WJ He, J Cao, J Chen… - Nutrition, Metabolism …, 2022 - Elsevier
Background and aims Identify novel metabolite associations with blood pressure (BP) salt-
sensitivity and hypertension. Methods and results The Genetic Epidemiology Network of Salt …

Urine metabolomics for assessing fertility-sparing treatment efficacy in endometrial cancer: a non-invasive approach using ultra-performance liquid chromatography …

J Chen, J Liu, D Cao - BMC Women's Health, 2023 - Springer
Objective This study aimed to reveal the urine metabolic change of endometrial cancer (EC)
patients during fertility-sparing treatment and establish non-invasive predictive models to …

Gut microbiota, blood metabolites, and left ventricular diastolic dysfunction in US Hispanics/Latinos

K Luo, A Taryn, EH Moon, BA Peters, SD Solomon… - Microbiome, 2024 - Springer
Background Left ventricular diastolic dysfunction (LVDD) is an important precursor of heart
failure (HF), but little is known about its relationship with gut dysbiosis and microbial-related …