Significance: The nuclear factor erythroid 2-related factor 2 (NRF2)-Kelch-like ECH-
associated protein 1 (KEAP1) system is a master regulator of redox homeostasis and cell …

The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome pathway is
mainly responsible for the activation and release of a cascade of proinflammatory mediators …

Hepatic fibrosis causes severe morbidity and death. No viable treatment can repair fibrosis
and protect the liver until now. We intended to discover the empagliflozin's (EMPA) …

Globally, inflammation and metabolic disorders pose serious public health problems and are
major health concerns. It has been shown that natural polyphenols are effective in the …

ABSTRACT Introduction Toxoplasma gondii, Trichomonas vaginalis, and Giardia intestinalis
are the causative agents of toxoplasmosis, trichomoniasis, and giardiasis, three important …

It is now established that patients with rheumatoid arthritis (RA) have an increased risk of
developing cervical cancer (CC) or its precursor, cervical intraepithelial neoplasia (CIN) …

Inflammasomes are multiprotein complexes that activate inflammatory responses by
inducing pyroptosis and secretion of pro-inflammatory cytokines. Along with many previous …

Normally, the host immunological response to viral infection is coordinated to restore
homeostasis and protect the individual from possible tissue damage. The two major …

Highlights•Legume-derived peptides can reduce cardiovascular diseases
progression.•Bioactive peptides activate novel pathways for cardiovascular diseases …

The increase in the world population along with new policies aimed at a more sustainable
world has led to the need of searching for new food sources, which are environmentally …