Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Collagen—emerging collagen based therapies hit the patient

EA Abou Neel, L Bozec, JC Knowles, O Syed… - Advanced drug delivery …, 2013 - Elsevier
The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

Accelerated mineralization of dense collagen-nano bioactive glass hybrid gels increases scaffold stiffness and regulates osteoblastic function

B Marelli, CE Ghezzi, D Mohn, WJ Stark, JE Barralet… - Biomaterials, 2011 - Elsevier
Plastically compressed dense collagen (DC) gels mimic the microstructural, mechanical,
and biological properties of native osteoid. This study investigated the effect of hybridizing …

Quantitative criteria to benchmark new and existing bio-inks for cell compatibility

K Dubbin, A Tabet, SC Heilshorn - Biofabrication, 2017 - iopscience.iop.org
Recent advancements in 3D bioprinting have led to the fabrication of more complex, more
precise, and larger printed tissue constructs. As the field continues to advance, it is critical to …

Osteogenic differentiation of human mesenchymal stem cells in a 3D woven scaffold

M Persson, PP Lehenkari, L Berglin, S Turunen… - Scientific reports, 2018 - nature.com
Fiber-based scaffolds produced by textile manufacturing technology offer versatile materials
for tissue engineering applications since a wide range of crucial scaffold parameters …

Effect of initial cell seeding density on early osteogenic signal expression of rat bone marrow stromal cells cultured on cross-linked poly (propylene fumarate) disks

K Kim, D Dean, AG Mikos, JP Fisher - Biomacromolecules, 2009 - ACS Publications
The intercellular signaling mechanisms among a transplanted cell population are largely
determined by the cell population itself as well as the surrounding environment. Changes in …

Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation

CA Mullen, MG Haugh, MB Schaffler… - Journal of the …, 2013 - Elsevier
Osteocytes are terminally differentiated bone cells, derived from osteoblasts, which are vital
for the regulation of bone formation and resorption. ECM stiffness and cell seeding density …

Mammalian and fish gelatin methacryloyl–alginate interpenetrating polymer network hydrogels for tissue engineering

C Ma, JB Choi, YS Jang, SY Kim, TS Bae, YK Kim… - ACS …, 2021 - ACS Publications
Gelatin methacryloyl (GelMA) has been widely studied as a biomaterial for tissue
engineering. Most studies focus on mammalian gelatin, but certain factors, such as …

Silk fibroin derived polypeptide-induced biomineralization of collagen

B Marelli, CE Ghezzi, A Alessandrino, JE Barralet… - Biomaterials, 2012 - Elsevier
Silk fibroin (SF) is extensively investigated in osteoregenerative therapy as it combines
extraordinary mechanical properties and directs calcium-phosphate formation. However, the …

Synergistic enhancement of human bone marrow stromal cell proliferation and osteogenic differentiation on BMP-2-derived and RGD peptide concentration gradients

NM Moore, NJ Lin, ND Gallant, ML Becker - Acta biomaterialia, 2011 - Elsevier
Rational design of bioactive tissue engineered scaffolds for directing bone regeneration in
vivo requires a comprehensive understanding of cell interactions with the immobilized …