The ability to cope with and adapt to changes in the environment is essential for all
organisms. Osmotic pressure is a universal threat when environmental changes result in an …

Highlights•Ion channels are central to biology and are found in all domains of
life.•Membrane-forming lipids were not generally thought to directly regulate channels.• …

Mechanosensitive ion channels transduce physical force into electrochemical signaling that
underlies an array of fundamental physiological processes, including hearing, touch …

Since life has emerged, gradients of osmolytes over the cell membrane cause pressure
changes in the cell and require tight regulation to prevent cell rupture. The …

Mechanosensitive (MS) channels are ubiquitous molecular force sensors that respond to a
number of different mechanical stimuli including tensile, compressive and shear stress. MS …

The small conductance mechanosensitive ion channel (MscS)-like (MSL) proteins in plants
are evolutionarily conserved homologs of the bacterial small conductance …

Mechanosensory transduction is defined as the ability of living cells to respond to a wide
variety of mechanical stimuli and convert them into electrical and/or biochemical intracellular …

The mechanosensitive channel of small conductance (MscS) is the prototype of an
evolutionarily diversified large family that fine-tunes osmoregulation but is likely to fulfill …

Secretins form multimeric channels across the outer membrane of Gram-negative bacteria
that mediate the import or export of substrates and/or extrusion of type IV pili. The secretin …

Mechanosensitive (MS) ion channels provide a universal mechanism for sensing and
responding to increased membrane tension. MscS‐like (MSL) 10 is a relatively well‐studied …