Microtubules (MTs) are highly dynamic polymers that constitute the cellular cytoskeleton and
play a role in multiple cellular functions. Variability characterizes biological systems and is …

Microtubules (MTs) are tubular polymers of tubulin that are highly dynamic and found
throughout the cytoplasm. MTs are involved in maintaining cell structure and, together with …

Plasma metabolite concentrations reflect the activity of tissue metabolic pathways and their
quantitative determination may be informative about pathogenic conditions. We searched for …

Protein phosphorylation-dephosphorylation events play a primary role in regulation of
almost all aspects of cell function including signal transduction, cell cycle, or apoptosis. Thus …

By promoting ceramide release at the cytosolic membrane leaflet, the neutral
sphingomyelinase 2 (NSM) is capable of organizing receptor and signalosome segregation …

EZH2 plays an essential role at the β-selection checkpoint of T lymphopoiesis by regulating
histone H3 lysine 27 trimethylation (H3K27me3) via its canonical mode of action. Increasing …

Introduction Microtubules are polymers that perform functions such as mitosis, intracellular
transport, cell morphology, and ciliary and flagellar motility. Since microtubules are taking …

Berichte aus der Literatur zeigen, dass im Tumormilieu verschiedene Faktoren akkumuliert
werden, die Einfluss auf T-Zellen ausüben können. Sollte das Tumormilieu inhibitorisch auf …