[HTML][HTML] Current strategies for brain drug delivery

X Dong - Theranostics, 2018 - ncbi.nlm.nih.gov
The blood-brain barrier (BBB) has been a great hurdle for brain drug delivery. The BBB in
healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …

A review on nanofluids: fabrication, stability, and thermophysical properties

N Ali, JA Teixeira, A Addali - Journal of Nanomaterials, 2018 - Wiley Online Library
Nanofluids have been receiving great attention in recent years due to their potential usage,
not only as an enhanced thermophysical heat transfer fluid but also because of their great …

RETRACTED ARTICLE: Nanofluids: properties and applications

GF Smaisim, DB Mohammed, AM Abdulhadi… - Journal of Sol-Gel …, 2022 - Springer
Nanofluids are liquid suspensions of hard nanometer-sized particles suspended in a base
fluid. The suspension of small solid particles in energy transmission fluids enhances their …

Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer's disease therapy

Y Zhou, F Zhu, Y Liu, M Zheng, Y Wang, D Zhang… - Science …, 2020 - science.org
Toxic aggregated amyloid-β accumulation is a key pathogenic event in Alzheimer's disease
(AD), which derives from amyloid precursor protein (APP) through sequential cleavage by …

Drug delivery challenges in brain disorders across the blood–brain barrier: novel methods and future considerations for improved therapy

A Achar, R Myers, C Ghosh - Biomedicines, 2021 - mdpi.com
Due to the physiological and structural properties of the blood–brain barrier (BBB), the
delivery of drugs to the brain poses a unique challenge in patients with central nervous …

Loss of lamin‐B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus

I Matias, LP Diniz, IV Damico, APB Araujo… - Aging cell, 2022 - Wiley Online Library
The increase in senescent cells in tissues, including the brain, is a general feature of normal
aging and age‐related pathologies. Senescent cells exhibit a specific phenotype, which …

Astrocyte senescence and Alzheimer's disease: a review

X Han, T Zhang, H Liu, Y Mi, X Gou - Frontiers in aging neuroscience, 2020 - frontiersin.org
Astrocytes are the largest group of glial cells in the brain and participate in several essential
functions of the central nervous system (CNS). Disruption of their normal physiological …

Glucose metabolism, neural cell senescence and Alzheimer's disease

Q Wang, L Duan, X Li, Y Wang, W Guo… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), an elderly neurodegenerative disorder with a high incidence and
progressive memory decline, is one of the most expensive, lethal, and burdening diseases …

Brain metabolic alterations in Alzheimer's disease

CG Ardanaz, MJ Ramírez, M Solas - International journal of molecular …, 2022 - mdpi.com
The brain is one of the most energy-consuming organs in the body. Satisfying such energy
demand requires compartmentalized, cell-specific metabolic processes, known to be …

Surface functionalization of metal and metal oxide nanoparticles for dispersion and tribological applications-a review

S Wang, D Chen, Q Hong, Y Gui, Y Cao, G Ren… - Journal of Molecular …, 2023 - Elsevier
Friction has caused a substantial amount of property damage in many industries worldwide,
and the continuous progress of industrial production requires the development of high …