The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Isolation and structure elucidation of most of the major cannabinoid constituents—including
Δ9-tetrahydrocannabinol (Δ9-THC), which is the principal psychoactive molecule in …

Two types of cannabinoid receptor have been discovered so far, CB1 (2.1: CBD: 1: CB1:),
cloned in 1990, and CB2 (2.1: CBD: 2: CB2:), cloned in 1993. Distinction between these …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

Cannabinoids have a long history of consumption for recreational and medical reasons. The
primary active constituent of the hemp plant Cannabis sativa is Δ9-tetrahydrocannabinol (Δ9 …

During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

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After their discovery, the two known cannabinoid receptors, CB1 and CB2, have been the
focus of research into the cellular signalling mechanisms of cannabinoids. The initial …

The cannabinoid receptor family currently includes twotypes: CB 1, characterized in
neuronal cells and brain, and CB 2, characterized in immune cells and tissues. CB 1 and CB …