Nanog, as a key cancer stem cell marker in tumor progression
Cancer stem cells (CSCs) are a small population of malignant cells that induce tumor onset
and development. CSCs share similar features with normal stem cells in the case of self …
and development. CSCs share similar features with normal stem cells in the case of self …
The dominant role of forkhead box proteins in cancer
Forkhead box (FOX) proteins are multifaceted transcription factors that are significantly
implicated in cancer, with various critical roles in biological processes. Herein, we provide …
implicated in cancer, with various critical roles in biological processes. Herein, we provide …
[HTML][HTML] Stemness-related markers in cancer
Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation
potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth …
potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth …
NANOG expression in human development and cancerogenesis
G Grubelnik, E Boštjančič, A Pavlič… - Experimental …, 2020 - journals.sagepub.com
NANOG is an important stem cell transcription factor involved in human development and
cancerogenesis. Its expression is complex and regulated on different levels. Moreover …
cancerogenesis. Its expression is complex and regulated on different levels. Moreover …
The hedgehog signaling networks in lung cancer: the mechanisms and roles in tumor progression and implications for cancer therapy
Y Abe, N Tanaka - BioMed research international, 2016 - Wiley Online Library
Lung cancer is the most common cause of cancer‐related death worldwide and is classified
into small cell lung cancer (SCLC) and non‐small‐cell lung cancer (NSCLC). Several gene …
into small cell lung cancer (SCLC) and non‐small‐cell lung cancer (NSCLC). Several gene …
FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21Cip1 CDK inhibitor
D Milewski, A Pradhan, X Wang, Y Cai, T Le, B Turpin… - Oncogene, 2017 - nature.com
Abstract The role of Forkhead Box F1 (FoxF1) transcription factor in carcinogenesis is not
well characterized. Depending on tissue and histological type of cancer, FoxF1 has been …
well characterized. Depending on tissue and histological type of cancer, FoxF1 has been …
Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer
A Benard, IJ Goossens-Beumer, AQ van Hoesel… - PloS one, 2014 - journals.plos.org
Numerous changes in epigenetic mechanisms have been described in various types of
tumors. In search for new biomarkers, we investigated the expression of Polycomb-group …
tumors. In search for new biomarkers, we investigated the expression of Polycomb-group …
[HTML][HTML] The emerging roles of forkhead box (FOX) proteins in osteosarcoma
W Zhang, N Duan, T Song, Z Li, C Zhang… - Journal of …, 2017 - ncbi.nlm.nih.gov
Osteosarcoma is the most common bone cancer primarily occurring in children and young
adults. Over the past few years, the deregulation of a superfamily transcription factors …
adults. Over the past few years, the deregulation of a superfamily transcription factors …
Genomic and epigenetic complexity of the FOXF1 locus in 16q24. 1: implications for development and disease
A V. Dharmadhikari, P Szafranski… - Current …, 2015 - benthamdirect.com
The FOXF1 (Forkhead box F1) gene, located on chromosome 16q24. 1 encodes a member
of the FOX family of transcription factors characterized by a distinct forkhead DNA binding …
of the FOX family of transcription factors characterized by a distinct forkhead DNA binding …
The prognostic value of whole blood, and mRNA expression in advanced small-cell lung cancer
Background. The data on expression and clinical impact of cancer stem cell markers SOX2,
NANOG and OCT4 in lung cancer is still lacking. The aim of our study was to compare …
NANOG and OCT4 in lung cancer is still lacking. The aim of our study was to compare …