Current status of stem cell therapies in tissue repair and regeneration

TK Giri, A Alexander, M Agrawal… - Current stem cell …, 2019 - ingentaconnect.com
Tissue engineering is a multi-disciplinary field such as material science, life science, and
bioengineering that are necessary to make artificial tissue or rejuvenate damaged tissue …

Multifunctional bioreactor system for human intestine tissues

W Zhou, Y Chen, T Roh, Y Lin, S Ling… - ACS Biomaterials …, 2018 - ACS Publications
The three-dimensional (3D) cultivation of intestinal cells and tissues in dynamic bioreactor
systems to represent in vivo intestinal microenvironments is essential for developing …

Prefabrication technique by preserving a muscular pedicle from masseter muscle as an in vivo bioreactor for reconstruction of mandibular critical‐sized bone defects …

H Nokhbatolfoghahaei, F Bastami… - … Research Part B …, 2022 - Wiley Online Library
In vivo bioreactors serve as regenerative niches that improve vascularization and
regeneration of bone grafts. This study has evaluated the masseter muscle as a natural …

Bioreactor cultivation condition for engineered bone tissue: effect of various bioreactor designs on extra cellular matrix synthesis

H Nokhbatolfoghahaei, M Bohlouli… - … Research Part A, 2020 - Wiley Online Library
Dynamic‐based systems are bio‐designed in order to mimic the micro‐environments of the
bone tissue. There is limited direct comparison between perfusion and perfusion‐rotation …

Computational modeling of media flow through perfusion-based bioreactors for bone tissue engineering

H Nokhbatolfoghahaei, M Bohlouli… - Proceedings of the …, 2020 - journals.sagepub.com
Bioreactor system has been used in bone tissue engineering in order to simulate dynamic
nature of bone tissue environments. Perfusion bioreactors have been reported as the most …

Towards self‐regulated bioprocessing: a compact benchtop bioreactor system for monitored and controlled 3D cell and tissue culture

S de Bournonville, T Lambrechts… - Biotechnology …, 2019 - Wiley Online Library
Bioreactors are crucial tools for the manufacturing of living cell‐based tissue engineered
products. However, to reach the market successfully, higher degrees of automation, as well …

Scaffold geometries designed to promote bone ingrowth by enhancing mechanobiological stimulation and biotransportation-a multiobjective optimisation approach

BM Ferguson, JR Clark, Q Li - Journal of the Mechanical Behavior of …, 2024 - Elsevier
In a tissue-engineered bone scaffold implant, the process of neo-tissue ingrowth and
remodelling into hard lamellar bone occurs slowly; it typically requires a period of several …

Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation

H Nokhbatolfoghahaei, S Baniameri, R Tabrizi… - In Vitro Cellular & …, 2024 - Springer
Vascularization is vital in bone tissue engineering, supporting development, remodeling,
and regeneration. Lack of vascularity leads to cell death, necessitating vascularization …

Co-cultivation of progenitor cells enhanced osteogenic gene expression and angiogenesis potential in vitro

Y Jia, C Zhang, X Zheng, M Gao - Journal of International …, 2021 - journals.sagepub.com
Objectives The efficiencies of osteogenesis and angiogenesis present challenges that need
to be overcome before bone tissue engineering can be widely applied to clinical uses. We …

A standardized and quality-controllable protocol of constructing individual tissue-engineered grafts applicable to treating large bone defects

J Xing, Y Lu, Y Cui, X Zhu, F Luo, Z Xie… - … Engineering Part C …, 2019 - liebertpub.com
Patient-specific individual tissue-engineered bones (iTEBs) have been recognized as a
promising strategy for treating large bone defects. However, current construction protocols of …