Functional network dysfunction in anxiety and anxiety disorders

CM Sylvester, M Corbetta, ME Raichle… - Trends in …, 2012 - cell.com
A recent paradigm shift in systems neuroscience is the division of the human brain into
functional networks. Functional networks are collections of brain regions with strongly …

Neuroscience of fear extinction: implications for assessment and treatment of fear-based and anxiety related disorders

MR Milad, BL Rosenbaum, NM Simon - Behaviour research and therapy, 2014 - Elsevier
Current exposure-based therapies aimed to reduce pathological fear and anxiety are now
amongst the most effective interventions for trauma and anxiety related disorders …

Hippocampal network connectivity and activation differentiates post-traumatic stress disorder from generalized anxiety disorder

AC Chen, A Etkin - Neuropsychopharmacology, 2013 - nature.com
Anxiety disorders are a diverse group of clinical states. Post-traumatic stress disorder
(PTSD) and generalized anxiety disorder (GAD), eg, share elevated anxiety symptoms, but …

Revise the revised? New dimensions of the neuroanatomical hypothesis of panic disorder

T Dresler, A Guhn, SV Tupak, AC Ehlis… - Journal of neural …, 2013 - Springer
In 2000, Gorman et al. published a widely acknowledged revised version of their 1989
neuroanatomical hypothesis of panic disorder (PD). Herein, a 'fear network'was suggested …

The effects of trauma on brain and body: A unifying role for the midbrain periaqueductal gray

BA Terpou, S Harricharan… - Journal of …, 2019 - Wiley Online Library
Post‐traumatic stress disorder (PTSD), a diagnosis that may follow the experience of trauma,
has multiple symptomatic phenotypes. Generally, individuals with PTSD display symptoms …

Neuroimaging of fear-associated learning

JA Greco, I Liberzon - Neuropsychopharmacology, 2016 - nature.com
Fear conditioning has been commonly used as a model of emotional learning in animals
and, with the introduction of functional neuroimaging techniques, has proven useful in …

Effect of cognitive-behavioral therapy on neural correlates of fear conditioning in panic disorder

T Kircher, V Arolt, A Jansen, M Pyka, I Reinhardt… - Biological …, 2013 - Elsevier
BACKGROUND: Learning by conditioning is a key ability of animals and humans for
acquiring novel behavior necessary for survival in a changing environment. Aberrant …

Predicting treatment response to cognitive behavioral therapy in panic disorder with agoraphobia by integrating local neural information

T Hahn, T Kircher, B Straube, HU Wittchen… - JAMA …, 2015 - jamanetwork.com
Importance Although neuroimaging research has made substantial progress in identifying
the large-scale neural substrate of anxiety disorders, its value for clinical application lags …

Neural substrates of treatment response to cognitive-behavioral therapy in panic disorder with agoraphobia

U Lueken, B Straube, C Konrad… - American Journal of …, 2013 - Am Psychiatric Assoc
Objective Although exposure-based cognitive-behavioral therapy (CBT) is an effective
treatment option for panic disorder with agoraphobia, the neural substrates of treatment …

Characterization of post-traumatic stress disorder using resting-state fMRI with a multi-level parametric classification approach

F Liu, B Xie, Y Wang, W Guo, JP Fouche, Z Long… - Brain topography, 2015 - Springer
Functional neuroimaging studies have found intra-regional activity and inter-regional
connectivity alterations in patients with post-traumatic stress disorder (PTSD). However, the …