Microfluidic strategies for the isolation and profiling of exosomes

J Bai, X Wei, X Zhang, C Wu, Z Wang, M Chen… - TrAC Trends in …, 2023 - Elsevier
Exosomes are nanoscale extracellular vesicles carrying various cargos, which play a
significant rule in intercellular communication, disease diagnosis and treatment …

Label-free microfluidic cell sorting and detection for rapid blood analysis

N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023 - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

Towards microfluidic-based exosome isolation and detection for tumor therapy

J Wang, P Ma, DH Kim, BF Liu, U Demirci - Nano Today, 2021 - Elsevier
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer
membrane structure of 30–150 nm in diameter. Their discovery and application have …

A review on comparative studies addressing exosome isolation methods from body fluids

TS Martins, M Vaz, AG Henriques - Analytical and Bioanalytical Chemistry, 2023 - Springer
Exosomes emerged as valuable sources of disease biomarkers and new therapeutic tools.
However, extracellular vesicles isolation with exosome-like characteristics from certain …

Acoustic microfluidics

P Zhang, H Bachman, A Ozcelik… - Annual Review of …, 2020 - annualreviews.org
Acoustic microfluidic devices are powerful tools that use sound waves to manipulate micro-
or nanoscale objects or fluids in analytical chemistry and biomedicine. Their simple device …

[HTML][HTML] Isolation of extracellular vesicles with combined enrichment methods

J Stam, S Bartel, R Bischoff, JC Wolters - Journal of Chromatography B, 2021 - Elsevier
Extracellular vesicles (EVs) are currently of tremendous interest in many research
disciplines and EVs have potential for development of EV diagnostics or therapeutics. Most …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

Methodologies to isolate and purify clinical grade extracellular vesicles for medical applications

A Akbar, F Malekian, N Baghban, SP Kodam, M Ullah - Cells, 2022 - mdpi.com
The use of extracellular vesicles (EV) in nano drug delivery has been demonstrated in many
previous studies. In this study, we discuss the sources of extracellular vesicles, including …

A sound approach to advancing healthcare systems: the future of biomedical acoustics

J Rufo, P Zhang, R Zhong, LP Lee, TJ Huang - Nature Communications, 2022 - nature.com
Newly developed acoustic technologies are playing a transformational role in life science
and biomedical applications ranging from the activation and inactivation of …

Multiphysics microfluidics for cell manipulation and separation: a review

H Cha, H Fallahi, Y Dai, D Yuan, H An, NT Nguyen… - Lab on a Chip, 2022 - pubs.rsc.org
Multiphysics microfluidics, which combines multiple functional physical processes in a
microfluidics platform, is an emerging research area that has attracted increasing interest for …