Mitochondrial roles and cytoprotection in chronic liver injury

D Degli Esposti, J Hamelin, N Bosselut… - Biochemistry …, 2012 - Wiley Online Library
The liver is one of the richest organs in terms of number and density of mitochondria. Most
chronic liver diseases are associated with the accumulation of damaged mitochondria …

Alveolar cell death in hyperoxia‐induced lung injury

A Pagano… - Annals of the New York …, 2003 - Wiley Online Library
Exposure to high oxygen concentration causes direct oxidative cell damage through
increased production of reactive oxygen species. In vivo oxygen‐induced lung injury is well …

Effect of low-protein diets on growth performance and body composition of broiler chicks

K Bregendahl, JL Sell, DR Zimmerman - Poultry science, 2002 - Elsevier
Three experiments were conducted to investigate effects of dietary manipulations to improve
growth performance and whole-body composition of broiler chicks fed low-protein diets …

In Vitro and In Vivo Studies Reveal that Hesperetin-7-O-glucoside, a Naturally Occurring Monoglucoside, Exhibits Strong Anti-inflammatory Capacity

F Wu, H Lei, G Chen, C Chen, Y Song… - Journal of agricultural …, 2021 - ACS Publications
Hesperetin-7-O-glucoside (Hes-7-G) is a naturally occurring flavonoid monoglucoside in
Citri Reticulatae Pericarpium and exhibits relatively high biological activities. To explore the …

Hyperoxia sensing: from molecular mechanisms to significance in disease

A Gore, M Muralidhar, MG Espey… - Journal of …, 2010 - Taylor & Francis
Oxygen therapy using mechanical ventilation with hyperoxia is necessary to treat patients
with respiratory failure and distress. However, prolonged exposure to hyperoxia leads to the …

Glutamine homeostasis and mitochondrial dynamics

JM Matés, JA Segura, JA Campos-Sandoval… - The international journal …, 2009 - Elsevier
Glutamine is a multifaceted amino acid that plays key roles in many metabolic pathways and
also fulfils essential signaling functions. Although classified as non-essential, recent …

Limitations to oxygen diffusion and equilibration in in vitro cell exposure systems in hyperoxia and hypoxia

CB Allen, BK Schneider… - American Journal of …, 2001 - journals.physiology.org
Exposure of cultured cells to changing gaseous environments is used as a model for
understanding both the immediate and long-term effects of such exposures on lung cells in …

[HTML][HTML] Hyperoxia decreases glycolytic capacity, glycolytic reserve and oxidative phosphorylation in MLE-12 cells and inhibits complex I and II function, but not …

KC Das - PloS one, 2013 - journals.plos.org
High levels of oxygen (hyperoxia) are frequently used in critical care units and in conditions
of respiratory insufficiencies in adults, as well as in infants. However, hyperoxia has been …

Therapeutic potential of glutathione-enhancers in stress-related psychopathologies

I Zalachoras, F Hollis, E Ramos-Fernández… - Neuroscience & …, 2020 - Elsevier
The mammalian brain has high energy demands, which may become higher in response to
environmental challenges such as psychogenic stress exposure. Therefore, efficient …

Lobetyolin induces apoptosis of colon cancer cells by inhibiting glutamine metabolism

W He, W Tao, F Zhang, Q Jie, Y He… - Journal of cellular …, 2020 - Wiley Online Library
The purpose of the present study was to evaluate the anti‐cancer property of Lobetyolin on
colorectal cancer and explore its potential mechanism. Lobetyolin was incubated with HCT …