The topic of this special issue on secondary versus idiopathic autism allows for discussion of
how different groups may come to manifest autism spectrum disorder (ASD) or ASD-like …

Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …

Neurodevelopmental disorders such as fragile X syndrome (FXS) result in lifelong cognitive
and behavioural deficits and represent a major public health burden. FXS is the most …

BACKGROUND AND OBJECTIVE: Individuals with fragile X syndrome (FXS) are frequently
codiagnosed with autism spectrum disorder (ASD). Most of our current knowledge about …

Autism spectrum disorder (ASD) is a severe neuropsychiatric disease with strong genetic
underpinnings. However, genetic contributions to autism are extremely heterogeneous, with …

Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and is
also linked to other neurologic and psychiatric disorders. FXS is caused by a triplet …

Background Population screening for FMR1 mutations has been a topic of considerable
discussion since the FMR1 gene was identified in 1991. Advances in understanding the …

Multiple sleep problems have been reported in children with Autism Spectrum Disorder
(ASD). The association of poor sleep with problematic daytime behaviors has been shown in …

Autism spectrum disorder (ASD) is a common comorbid condition in people with fragile X
syndrome (FXS). It has been assumed that ASD symptoms reflect the same underlying …

Despite early controversy, it is now accepted that a substantial proportion of children with
fragile X syndrome (FXS) meets diagnostic criteria for autism spectrum disorder (ASD). This …