Significance: After three decades, more than 75,000 publications, tens of companies being
involved in its commercialization, and a global market perspective of about USD 1.5 billion …

Quantification of chromophore concentrations in reflectance mode remains a major
challenge for biomedical optics. Spectroscopic Optical Coherence Tomography (SOCT) …

A thorough understanding of the spatiotemporal dynamics of blood supply and tissue
viability is of great importance in stroke researches. In the current study, vascular and …

Background Retinal oxygen saturation (sO2) provides essential information about the eye's
response to pathological changes that can result in vision loss. Visible-light optical …

Photo-thermal optical coherence tomography (PT-OCT) is a functional extension of
conventional OCT with the ability to generate maps of light absorption co-registered with the …

Photothermal optical coherence tomography (PT-OCT) is an emerging extension of OCT,
which forms images based on both scattering and absorption of light. The speed of PT-OCT …

Multispectral imaging (MSI) is a technique for measurement of blood oxygen saturation in
vivo that can be applied using various imaging modalities to provide new insights into …

Photothermal OCT (PTOCT) provides high sensitivity to molecular targets in tissue, and
occupies a spatial imaging regime that is attractive for small animal imaging. However …

The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in
tissue. A sub-micrometer scale displacement occurs within a few microseconds after the …

We present our work on examining the feasibility of monitoring photodynamic therapy (PDT)-
induced vasculature change with acoustic-resolution photoacoustic microscopy (PAM) …