The complete genomes of three strains from the phylum Acidobacteria were compared.
Phylogenetic analysis placed them as a unique phylum. They share genomic traits with …

Family GH13, also known as the α-amylase family, is the largest sequence-based family of
glycoside hydrolases and groups together a number of different enzyme activities and …

Carbohydrate-active enzymes face huge substrate diversity in a highly selective manner
using only a limited number of available folds. They are therefore subjected to multiple …

Multiple comparison or alignmentof protein sequences has become a fundamental tool in
many different domains in modern molecular biology, from evolutionary studies to prediction …

Specificity-determining sites (SDS) are the key positions of a protein family that show a
specific conservation of amino acids, related to the subfamily members of that family. SDS …

Abstract Over 1,600 genes encoding carbohydrate-active enzymes (CAZymes) in the
Populus trichocarpa (Torr. & Gray) genome were identified based on sequence homology …

Phylogenomic inference of protein (or gene) function attempts to address the question,''What
function does this protein perform?''in an evolutionary context. As originally outlined by …

Alcohol oxidases, including carbohydrate oxidases, have a long history of research that has
generated fundamental biological understanding and biotechnological applications. Despite …

Understanding the determinants of virus transmission is a fundamental step for effective
design of screening and intervention strategies to control viral epidemics. Phylogenetic …

Motivation: Most multiple sequence alignment programs use heuristics that sometimes
introduce errors into the alignment. The most commonly used methods to correct these …