Irritable bowel syndrome (IBS) is a complex, functional gastrointestinal disorder
characterized by chronic abdominal pain or discomfort and altered bowel habits. Despite the …

Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …

Functional bowel disorders are highly prevalent disorders found worldwide. These disorders
have the potential to affect all members of society, regardless of age, sex, race, creed, color …

The past decade has witnessed an explosion of knowledge regarding the vast microbial
community that resides within our intestine—the gut microbiota. The topic has generated …

Functional gastrointestinal disorders—recently renamed into disorders of gut–brain
interaction—such as irritable bowel syndrome and functional dyspepsia are highly prevalent …

IBS is one of the most common functional gastrointestinal disorders worldwide and is
thought to be the result of disturbed neural function along the brain–gut axis. The …

BACKGROUND: Subtle histopathologic features such as eosinophilia and increased mast
cells have been observed in functional gastrointestinal disorders (FGIDs), including …

Abstract Background & Aims Increases in mucosal immune cells have frequently been
observed in irritable bowel syndrome (IBS) patients. However, this finding is not completely …

Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders,
characterized by abdominal pain, bloating, and changes in bowel habits. These symptoms …

Background Irritable bowel syndrome (IBS), one of the most common gastrointestinal
disorders, markedly impairing patients' quality of life. Drug development for IBS treatment …