Natural killer cell specificity for viral infections

Q Hammer, T Rückert, C Romagnani - Nature immunology, 2018 - nature.com
Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …

NK cell recognition

LL Lanier - Annu. Rev. Immunol., 2005 - annualreviews.org
NK CELL RECOGNITION | Annual Reviews Menu Publications AZ Journal Information About
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Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells

Q Hammer, T Rückert, EM Borst, J Dunst… - Nature …, 2018 - nature.com
Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …

Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection

S Lopez-Vergès, JM Milush… - Proceedings of the …, 2011 - National Acad Sciences
During human CMV infection, there is a preferential expansion of natural killer (NK) cells
expressing the activating CD94–NKG2C receptor complex, implicating this receptor in the …

The NKG2A–HLA-E axis as a novel checkpoint in the tumor microenvironment

L Borst, SH van der Burg, T van Hall - Clinical cancer research, 2020 - AACR
The success of checkpoint blockade therapy revolutionized cancer treatment. However, we
need to increase the fraction of responding patients and overcome acquired resistance to …

Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts

M Gumá, M Budt, A Sáez, T Brckalo, H Hengel… - Blood, 2006 - ashpublications.org
CD94/NKG2C+ natural killer (NK) cells are increased in healthy individuals infected with
human cytomegalovirus (HCMV), suggesting that HCMV infection may shape the NK cell …

Evolutionary struggles between NK cells and viruses

LL Lanier - Nature Reviews Immunology, 2008 - nature.com
Natural killer (NK) cells are well recognized for their ability to provide a first line of defence
against viral pathogens and they are increasingly being implicated in immune responses …

Programming cytomegalovirus as an HIV vaccine

LJ Picker, JD Lifson, M Gale, SG Hansen, K Früh - Trends in immunology, 2023 - cell.com
The initial development of cytomegalovirus (CMV) as a vaccine vector for HIV/simian
immunodeficiency virus (SIV) was predicated on its potential to pre-position high-frequency …

Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus

TI Arnon, H Achdout, O Levi, G Markel, N Saleh… - Nature …, 2005 - nature.com
Human cytomegalovirus, a chief pathogen in immunocompromised people, can persist in a
healthy immunocompetent host throughout life without being eliminated by the immune …

Modulation of innate and adaptive immunity by cytomegaloviruses

R Berry, GM Watson, S Jonjic… - Nature reviews …, 2020 - nature.com
The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …