Aspirin and P2Y12 antagonists are commonly used anti‐platelet agents. Aspirin produces its
effects through inhibition of thromboxane A2 (TXA2) production, while P2Y12 antagonists …

There is compelling evidence to support an aetiological role for inflammation, oxidative and
nitrosative stress (O&NS), and mitochondrial dysfunction in the pathophysiology of major …

This article provides a theoretical overview of the association between age-related hearing
loss (ARHL), immune system ageing (immunosenescence), and chronic inflammation …

Areas timely for developing research: Extensive research is under way to identify additional
novel serum markers with higher specificity for coronary artery plaque inflammation. Specific …

Importance Depression is associated with increased inflammation, which may precede its
onset, especially in older people. Some preclinical data suggest potential antidepressant …

Chronic inflammation, which is associated with obesity, may play a role in the etiology of
several diseases. Thus, reducing inflammation may offer a disease-prevention strategy …

Laboratory evidence suggests that certain specialty dietary supplements have
antiinflammatory properties, though evidence in humans remains limited. Data on a …

Metabolic syndrome (MetS), a cluster of dyslipidaemia, central obesity, hypertension and/or
insulin resistance, is associated with increased cardiovascular disease (CVD) type 2 …

The slow accumulation of inflammatory biomarker levels in the body—also known as
inflammaging—has been linked to a myriad of age-related diseases. Some of these include …

Four large trials have recently evaluated the effects of anti-inflammatory drugs in the
secondary prevention of major cardiovascular events (MACE) in over 25 000 patients …