Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …

DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …

" Across diverse disciplines, the term resilience is appearing more and more often. However,
while each discipline has developed theory and models to explain the resilience of the …

Consistent failure over the past few decades to reduce the high prevalence of stress-related
disorders has motivated a search for alternative research strategies. Resilience refers to the …

The process of aging results in a host of changes at the cellular and molecular levels, which
include senescence, telomere shortening, and changes in gene expression. Epigenetic …

Resilience is still often viewed as a unitary personality construct that, as a kind of
antinosological entity, protects individuals against stress-related mental problems. However …

Background. Infection with human immunodeficiency virus type 1 (HIV) is associated with
clinical symptoms of accelerated aging, as evidenced by the increased incidence and …

Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …

HIV-infected individuals are living longer on antiretroviral therapy, but many patients display
signs that in some ways resemble premature aging. To investigate and quantify the impact of …

Early adversity, in the form of abuse, neglect, socioeconomic status and other adverse
experiences, is associated with poor physical and mental health outcomes. To understand …