Constitutive modeling of brain tissue: current perspectives

R de Rooij, E Kuhl - Applied Mechanics Reviews, 2016 - asmedigitalcollection.asme.org
Modeling the mechanical response of the brain has become increasingly important over the
past decades. Although mechanical stimuli to the brain are small under physiological …

Neuromechanics: from neurons to brain

A Goriely, S Budday, E Kuhl - Advances in applied mechanics, 2015 - Elsevier
Arguably, the brain is the most complex organ in the human body, and, at the same time, the
least well understood. Today, more than ever before, the human brain has become a subject …

Brain stiffness increases with myelin content

J Weickenmeier, R de Rooij, S Budday, P Steinmann… - Acta biomaterialia, 2016 - Elsevier
Brain stiffness plays an important role in neuronal development and disease, but reported
stiffness values vary significantly for different species, for different brains, and even for …

Multiphysics of prionlike diseases: Progression and atrophy

J Weickenmeier, E Kuhl, A Goriely - Physical review letters, 2018 - APS
Many neurodegenerative diseases are related to the propagation and accumulation of toxic
proteins throughout the brain. The lesions created by aggregates of these toxic proteins …

Elasticity of fibrous networks under uniaxial prestress

M Vahabi, A Sharma, AJ Licup, ASG Van Oosten… - Soft matter, 2016 - pubs.rsc.org
We present theoretical and experimental studies of the elastic response of fibrous networks
subjected to uniaxial strain. Uniaxial compression or extension is applied to extracellular …

The mechanics of decompressive craniectomy: Personalized simulations

J Weickenmeier, CAM Butler, PG Young… - Computer Methods in …, 2017 - Elsevier
Decompressive craniectomy is a traditional but controversial surgical procedure that
removes part of the skull to allow an injured and swollen brain to expand outward. Recent …

Transcranial focused ultrasound generates skull-conducted shear waves: Computational model and implications for neuromodulation

H Salahshoor, MG Shapiro, M Ortiz - Applied Physics Letters, 2020 - pubs.aip.org
Focused ultrasound (FUS) is an established technique for non-invasive surgery and has
recently attracted considerable attention as a potential method for non-invasive …

Electrical Stimulation of Human Mesenchymal Stem Cells on Conductive Substrates Promotes Neural Priming

BS Eftekhari, D Song, PA Janmey - Macromolecular bioscience, 2023 - Wiley Online Library
Electrical stimulation (ES) within a conductive scaffold is potentially beneficial in
encouraging the differentiation of stem cells toward a neuronal phenotype. To improve stem …

[HTML][HTML] Cell-induced confinement effects in soft tissue mechanics

D Song, JL Shivers, FC MacKintosh… - Journal of Applied …, 2021 - pubs.aip.org
The mechanical properties of tissues play a critical role in their normal and
pathophysiological functions such as tissue development, aging, injury, and disease …

[HTML][HTML] Materials science and mechanosensitivity of living matter

AE Patteson, ME Asp, PA Janmey - Applied Physics Reviews, 2022 - pubs.aip.org
Living systems are composed of molecules that are synthesized by cells that use energy
sources within their surroundings to create fascinating materials that have mechanical …