Dimerization of retroviral RNA genomes: an inseparable pair
JC Paillart, M Shehu-Xhilaga, R Marquet… - Nature Reviews …, 2004 - nature.com
Many viruses carry more than one segment of nucleic acid into the virion particle, but
retroviruses are the only known group of viruses that contain two identical (or nearly …
retroviruses are the only known group of viruses that contain two identical (or nearly …
The life-cycle of the HIV-1 Gag–RNA complex
E Mailler, S Bernacchi, R Marquet, JC Paillart… - Viruses, 2016 - mdpi.com
Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process
requiring the recruitment of viral and cellular components to the plasma membrane for …
requiring the recruitment of viral and cellular components to the plasma membrane for …
Retroviral RNA dimerization: from structure to functions
N Dubois, R Marquet, JC Paillart… - Frontiers in …, 2018 - frontiersin.org
The genome of the retroviruses is a dimer composed by two homologous copies of genomic
RNA (gRNA) molecules of positive polarity. The dimerization process allows two gRNA …
RNA (gRNA) molecules of positive polarity. The dimerization process allows two gRNA …
HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein
Retroviruses package a dimeric genome comprising two copies of the viral RNA. Each RNA
contains all of the genetic information for viral replication. Packaging a dimeric genome …
contains all of the genetic information for viral replication. Packaging a dimeric genome …
[HTML][HTML] Understanding retroviral life cycle and its genomic RNA packaging
Members of the family Retroviridae are important animal and human pathogens. Being
obligate parasites, their replication involves a series of steps during which the virus hijacks …
obligate parasites, their replication involves a series of steps during which the virus hijacks …
Dimeric RNA recognition regulates HIV-1 genome packaging
OA Nikolaitchik, KA Dilley, W Fu, RJ Gorelick… - PLoS …, 2013 - journals.plos.org
How retroviruses regulate the amount of RNA genome packaged into each virion has
remained a long-standing question. Our previous study showed that most HIV-1 particles …
remained a long-standing question. Our previous study showed that most HIV-1 particles …
Dual role of the lymphocytic choriomeningitis virus intergenic region in transcription termination and virus propagation
DD Pinschewer, M Perez, JC de la Torre - Journal of virology, 2005 - Am Soc Microbiol
Each genome segment of the prototypic arenavirus lymphocytic choriomeningitis virus
(LCMV), encodes two genes in ambisense orientation, separated by an intergenic region …
(LCMV), encodes two genes in ambisense orientation, separated by an intergenic region …
HIV controls the selective packaging of genomic, spliced viral and cellular RNAs into virions through different mechanisms
L Houzet, JC Paillart, F Smagulova… - Nucleic acids …, 2007 - academic.oup.com
In addition to genomic RNA, HIV-1 particles package cellular and spliced viral RNAs. In
order to determine the encapsidation mechanisms of these RNAs, we determined the …
order to determine the encapsidation mechanisms of these RNAs, we determined the …
HIV-1 RNA genome packaging: it's G-rated
A Duchon, WS Hu - Mbio, 2024 - Am Soc Microbiol
ABSTRACT A member of the Retroviridae, human immunodeficiency virus type 1 (HIV-1),
uses the RNA genome packaged into nascent virions to transfer genetic information to its …
uses the RNA genome packaged into nascent virions to transfer genetic information to its …
A riboswitch regulates RNA dimerization and packaging in human immunodeficiency virus type 1 virions
The genome of retroviruses, including human immunodeficiency virus type 1 (HIV-1),
consists of two identical RNA strands that are packaged as noncovalently linked dimers. The …
consists of two identical RNA strands that are packaged as noncovalently linked dimers. The …