Almost all polymerase II transcripts undergo alternative pre-mRNA splicing. Here, we review
the functions of alternative splicing events that have been experimentally determined. The …

Introduction: Enhancement of glucose metabolism and repression of oxidative
phosphorylation followed by the Warburg effect is the common hallmark of cancer cells …

Here, we present APPRIS (http://appris. bioinfo. cnio. es), a database that houses
annotations of human splice isoforms. APPRIS has been designed to provide value to …

Abstract The APPRIS database (http://appris-tools. org) uses protein structural and functional
features and information from cross-species conservation to annotate splice isoforms in …

Abstract APPRIS (https://appris. bioinfo. cnio. es) is a well-established database housing
annotations for protein isoforms for a range of species. APPRIS selects principal isoforms …

A comprehensive knowledge of all the factors involved in splicing, both proteins and RNAs,
and of their interaction network is crucial for reaching a better understanding of this process …

Recent advances in long-read sequencing solve inaccuracies in alternative transcript
identification of full-length transcripts in short-read RNA-Seq data, which encourages the …

Background The study of RNA has been dramatically improved by the introduction of Next
Generation Sequencing platforms allowing massive and cheap sequencing of selected RNA …

The development of novel high-throughput sequencing (HTS) methods for RNA (RNA-Seq)
has provided a very powerful mean to study splicing under multiple conditions at …

Alternative splicing is a major contributor to cellular diversity. Therefore the identification and
quantification of differentially spliced transcripts in genome-wide transcript analysis is an …