The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that
share structural and functional similarities and possess potent superantigenic activity …

This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …

Bacterial sepsis is a major cause of fatality worldwide. Sepsis is a multi-step process that
involves an uncontrolled inflammatory response by the host cells that may result in multi …

▪ Abstract Toxic shock syndrome (TSS) is an acute onset illness characterized by fever, rash
formation, and hypotension that can lead to multiple organ failure and lethal shock, as well …

The number and diversity of surface plasmon resonance (SPR) biosensor applications
continue to increase. Evolutions in instrument and sensor chip technology, experimental …

Superantigens (SAgs) are the most powerful T cell mitogens ever discovered.
Concentrations of less than 0· 1 pg/ml of a bacterial superantigen are sufficient to stimulate …

Superantigens are unconventional antigens which recognise immune receptors outside
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …

Superantigens (SAgs) are potent exotoxins secreted by Staphylococcus aureus and
Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a …

The design of an ideal scoring function for protein− protein docking that would also predict
the binding affinity of a complex is one of the challenges in structural proteomics. Such a …

▪ Abstract Superantigens (SAGs) are a class of immunostimulatory and disease-causing
proteins of bacterial or viral origin with the ability to activate large fractions (5–20%) of the T …