Background Traumatic brain injury poses an enormous clinical challenge. Rats are the
animals most widely used in pre-clinical experiments. Biomechanical simulations of these …

Traumatic brain injuries, the leading cause of death and disability in children and young
adults, are the result of a rapid acceleration or impact of the head. In recent years, a global …

Acute subdural hematoma (ASDH) caused by bridging vein (BV) rupture is a frequent and
lethal brain injury, especially in the elderly. Brain atrophy has been hypothesized to be a …

Traumatic brain injury (TBI) can occur at any age, from youth to the elderly, and its
contribution to age-related neuropathology remains unknown. Few studies have …

Diffuse axonal injury (DAI) is a severe form of traumatic brain injury and often induced by
blunt trauma. The closed head impact acceleration (IA) model is the most widely used rodent …

Traumatic brain injury (TBI) commonly results in primary diffuse axonal injury (DAI) and
associated secondary injuries that evolve through a cascade of pathological mechanisms …

Background Skull fracture can lead to significant morbidity and mortality, yet the
development of effective predictive tools has remained a challenge. This study aimed to …

Traumatic brain injury (TBI) can affect individuals at any age, with the potential of causing
lasting neurologic consequences. The lack of effective therapeutic solutions and …

Concussion, in spite of being a mild traumatic brain injury, involves serious long term
consequences and can adversely affect the life of an individual, their family and the wider …

Acute spinal cord injuries (SCI) have a global annual occurrence rate of 14 to 40 per million
population with considerable societal cost. The primary mechanism of injury involves …