Fasciola and fasciolosis in ruminants in Europe: Identifying research needs

NJ Beesley, C Caminade, J Charlier… - Transboundary and …, 2018 - Wiley Online Library
Fasciola hepatica is a trematode parasite with a global distribution, which is responsible for
considerable disease and production losses in a range of food producing species. It is also …

Liver fluke vaccines in ruminants: strategies, progress and future opportunities

H Toet, DM Piedrafita, TW Spithill - International journal for parasitology, 2014 - Elsevier
The development of a vaccine for Fasciola spp. in livestock is a challenge and would be
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …

Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults

DJ Diemert, J Freire, V Valente, CG Fraga… - PLoS neglected …, 2017 - journals.plos.org
Necator americanus Glutathione-S-Transferase-1 (Na-GST-1) plays a role in the digestion of
host hemoglobin by adult N. americanus hookworms. Vaccination of laboratory animals with …

Fasciolosis in India: an overview

H Lalrinkima, C Lalchhandama, SS Jacob… - Experimental …, 2021 - Elsevier
Fasciolosis in ruminants is a relentless constraint in the livestock industry across the world.
Immuno-prophylactic vaccines against fasciolosis may not come up in near future, rendering …

Development of the Brazilian anti schistosomiasis vaccine based on the recombinant fatty acid binding protein Sm14 plus GLA-SE adjuvant

M Tendler, M Almeida, A Simpson - Frontiers in immunology, 2015 - frontiersin.org
Data herein reported and discussed refer to vaccination with the recombinant fatty acid
binding protein (FABP) family member of the schistosomes, called Sm14. This antigen was …

Fasciolosis: pathogenesis, host-parasite interactions, and implication in vaccine development

LM Flores-Velázquez, MT Ruiz-Campillo… - Frontiers in Veterinary …, 2023 - frontiersin.org
Fasciola hepatica is distributed worldwide, causing substantial economic losses in the
animal husbandry industry. Human fasciolosis is an emerging zoonosis in Andean America …

Juvenile-specific cathepsin proteases in Fasciola spp.: their characteristics and vaccine efficacies

K Meemon, P Sobhon - Parasitology Research, 2015 - Springer
Fasciolosis, caused by Fasciola hepatica and Fasciola gigantica, is one of the most
neglected tropical zoonotic diseases. One sustainable control strategy against these …

Early hepatic and peritoneal changes and immune response in goats vaccinated with a recombinant glutathione transferase sigma class and challenged with Fasciola …

R Zafra, RA Perez-Ecija, L Buffoni, IL Pacheco… - Research in Veterinary …, 2013 - Elsevier
Abstract Changes and local immune response were evaluated in the peritoneal cell
populations, duodenal lamina propria and liver from goats immunized with recombinant …

Assessment of Fasciola hepatica glutathione S-transferase as an antigen for serodiagnosis of human chronic fascioliasis

V Aguayo, B Valdes, AM Espino - Acta tropica, 2018 - Elsevier
Due to the unsatisfactory performance of parasitological diagnosis of human fascioliasis; the
use of immunodiagnosis based on the detection of anti-Fasciola antibodies is traditionally …

Transcriptomic responses of water buffalo liver to infection with the digenetic fluke Fasciola gigantica

FK Zhang, XX Zhang, HM Elsheikha, JJ He… - Parasites & …, 2017 - Springer
Background Fasciola gigantica, the tropical liver fluke, infects buffaloes in Asian and African
countries and causes significant economic losses and poses public health threat in these …