Screening of the Pandemic Response Box library identified promising compound candidate drug combinations against extensively drug-resistant Acinetobacter …

N Boonyalai, D Peerapongpaisarn, C Thamnurak… - Scientific Reports, 2024 - nature.com
Infections caused by antimicrobial-resistant Acinetobacter baumannii pose a significant
threat to human health, particularly in the context of hospital-acquired infections. As existing …

[HTML][HTML] Investigating the Antimicrobial Potential of 560 Compounds from the Pandemic Response Box and COVID Box against Resistant Gram-Negative Bacteria

RC Cerqueira Melo, AA Martins, ALF Melo… - Antibiotics, 2024 - mdpi.com
Antimicrobial resistance (AMR) has emerged as a significant threat to public health,
particularly in infections caused by critically important Gram-negative bacteria. The …

The effect of epetraborole on the transcriptome and proteome profiles of an Escherichia coli strain overexpressing leuS, Leucyl-tRNA Synthetase

A Babayeva, E Dibek, DS Akkoyunlu… - Frontiers in Life …, 2024 - dergipark.org.tr
Epetraborole (EP) is a boron-containing antibiotic known for its effectiveness against gram-
negative enteric bacteria and Mycobacterium species. It is designed to bind and inhibit the …