Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Background Having a penicillin allergy label associates with a higher risk for antibiotic
resistance and increased health care use. Objective We sought to assess the accuracy of …

A recent survey of the European Academy of Allergy and Clinical Immunology (EAACI) Drug
Allergy Interest Group (DAIG) on how European allergy specialists deal with beta‐lactam …

Drug hypersensitivity reactions (DHRs) are nowadays the third cause of allergy after rhinitis
and asthma with a significant increase in prevalence in both adults and paediatric …

Background The diagnosis of allergic reactions to penicillins (AR‐PEN) is very complex as
there is a loss of sensitization over time, which leads to negative skin tests (STs) and specific …

Background Patients with a penicillin allergy label tend to have worse clinical outcomes and
increased healthcare use. Drug provocation tests (DPT) are the gold‐standard in the …

Since overdiagnosis of beta‐lactam (BL) allergy is common in the pediatric population,
delabeling is a critical part of antimicrobial stewardship. Undesirable consequences of …

Background Immediate hypersensitivity reactions to penicillins are often labeled on the
basis of a similar set of symptoms, but a key feature of these reactions that can be …

Background An accurate diagnosis of β-lactam (BL) allergy improves the use of antibiotics,
increases patients' safety, and reduces costs to health systems. Nevertheless, it requires …

Drug provocation test (DPT) is the controlled administration of a drug to diagnose immune-or
non-immune-mediated drug hypersensitivity and the last step for accurate recognition of …