Disease resistance mechanisms in plants

EJ Andersen, S Ali, E Byamukama, Y Yen, MP Nepal - Genes, 2018 - mdpi.com
Plants have developed a complex defense system against diverse pests and pathogens.
Once pathogens overcome mechanical barriers to infection, plant receptors initiate signaling …

How to build a pathogen detector: structural basis of NB-LRR function

FLW Takken, A Goverse - Current opinion in plant biology, 2012 - Elsevier
Many plant disease resistance (R) proteins belong to the family of nucleotide-binding-
leucine rich repeat (NB-LRR) proteins. NB-LRRs mediate recognition of pathogen-derived …

Wheat Pm4 resistance to powdery mildew is controlled by alternative splice variants encoding chimeric proteins

J Sánchez-Martín, V Widrig, G Herren, T Wicker… - Nature Plants, 2021 - nature.com
Crop breeding for resistance to pathogens largely relies on genes encoding receptors that
confer race-specific immunity. Here, we report the identification of the wheat Pm4 race …

Identification of Wheat Gene Sr35 That Confers Resistance to Ug99 Stem Rust Race Group

C Saintenac, W Zhang, A Salcedo, MN Rouse… - Science, 2013 - science.org
Wheat stem rust, caused by Puccinia graminis f. sp. tritici (Pgt), is a devastating disease that
can cause severe yield losses. A previously uncharacterized Pgt race, designated Ug99 …

Wheat gene Sr60 encodes a protein with two putative kinase domains that confers resistance to stem rust

S Chen, MN Rouse, W Zhang, X Zhang, Y Guo… - New …, 2020 - Wiley Online Library
Wheat stem rust, caused by Puccinia graminis Pers. f. sp. tritici (Pgt), is a devastating fungal
disease threatening global wheat production. The present paper reports the identification of …

Impacts of resistance gene genetics, function, and evolution on a durable future

RW Michelmore, M Christopoulou… - Annual review of …, 2013 - annualreviews.org
Studies on resistance gene function and evolution lie at the confluence of structural and
molecular biology, genetics, and plant breeding. However, knowledge from these disparate …

Identification and characterization of wheat stem rust resistance gene Sr21 effective against the Ug99 race group at high temperature

S Chen, W Zhang, S Bolus, MN Rouse… - PLoS genetics, 2018 - journals.plos.org
Wheat stem rust, caused by Puccinia graminis f. sp. tritici (Pgt), is a devastating foliar
disease. The Ug99 race group has combined virulence to most stem rust (Sr) resistance …

Transcript‐level expression control of plant NLR genes

Y Lai, T Eulgem - Molecular plant pathology, 2018 - Wiley Online Library
Plant NLR genes encode sensitive immune receptors that can mediate the specific
recognition of pathogen avirulence effectors and activate a strong defence response, termed …

Alternative splicing in plant immunity

S Yang, F Tang, H Zhu - International journal of molecular sciences, 2014 - mdpi.com
Alternative splicing (AS) occurs widely in plants and can provide the main source of
transcriptome and proteome diversity in an organism. AS functions in a range of …

Wheat disease resistance genes and their diversification through integrated domain fusions

EJ Andersen, MP Nepal, JM Purintun, D Nelson… - Frontiers in …, 2020 - frontiersin.org
Plants are in a constant evolutionary arms race with their pathogens. At the molecular level,
the plant nucleotide-binding leucine-rich repeat receptors (NLRs) family has coevolved with …