Mucoadhesive drug delivery systems are desirable as they can increase the residence time
of drugs at the site of absorption/action, provide sustained drug release and minimize the …

There is an obvious need for efficient and safe nasal absorption enhancers for the
development of therapeutically efficacious nasal products for small hydrophilic drugs …

Nowadays, tissue and organ failures resulted from injury, aging accounts, diseases or other
type of damages is one of the most important health problems with an increasing incidence …

Nanomaterials based on chitosan have emerged as promising carriers of therapeutic agents
for drug delivery due to good biocompatibility, biodegradability, and low toxicity. Chitosan …

Chitosan is a nontoxic, biodegradable, and biocompatible polysaccharide of β (1-4)-linked d-
glucosamine and N-acetyl-d-glucosamine. This derivative of natural chitin presents …

This review sets out to describe and discuss the synthetic approaches and the fields of
application of PEGylated chitosan copolymers especially for medical use. The PEGylation of …

Natural polysaccharides are frequently used in the design of drug delivery systems due to
their biocompatibility, biodegradability, and low toxicity. Moreover, they are diverse in …

The prevention and treatment of cardiovascular diseases (CVD) has largely focused on
lowering circulating LDL cholesterol, yet a significant burden of atherosclerotic disease …

Transmucosal administration offers numerous advantages for drug delivery as it usually
helps to avoid first pass metabolism, provides rapid onset of action, and is a non-invasive …

This study aims at developing chitosan-based nanoparticles suitable for an intravenous
administration of small interfering RNA (siRNA) able to achieve (i) high gene silencing …