Mitochondrial DNA as inflammatory DAMP: a warning of an aging immune system?
G Zanini, V Selleri, S Lopez Domenech… - Biochemical Society …, 2023 - portlandpress.com
Senescence of the immune system is characterized by a state of chronic, subclinical, low-
grade inflammation termed 'inflammaging', with increased levels of proinflammatory …
grade inflammation termed 'inflammaging', with increased levels of proinflammatory …
[HTML][HTML] Mitochondria during T cell aging
JI Escrig-Larena, S Delgado-Pulido… - Seminars in Immunology, 2023 - Elsevier
Mitochondrial dysfunction is a hallmark of aging that contributes to inflammaging. It is
characterized by alterations of the mitochondrial DNA, reduced respiratory capacity …
characterized by alterations of the mitochondrial DNA, reduced respiratory capacity …
Increased levels of circulating cell-free DNA in COVID-19 patients with respiratory failure
A Tanaka, K Wakayama, Y Fukuda, S Ohta… - Scientific Reports, 2024 - nature.com
Cell-free DNA (cfDNA) is released from injured cells and aggravates inflammation. Patients
with coronavirus disease (COVID-19) often develop pneumonia and respiratory failure, and …
with coronavirus disease (COVID-19) often develop pneumonia and respiratory failure, and …
Plasma extracellular vesicles and cell-free mitochondrial DNA are associated with cognitive dysfunction in treated older adults with HIV
CD Johnston, EGM de Menezes, S Bowler… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nanoparticles with a role in intercellular communication. Cell-
free mitochondrial DNA (cf-mtDNA) has been associated with cognitive dysfunction in …
free mitochondrial DNA (cf-mtDNA) has been associated with cognitive dysfunction in …
Recovery from intensive care unit acquired muscle weakness (ICUAW): molecular determinants and consequences for physical recovery and quality of life in patients …
A Thomas - 2023 - qmro.qmul.ac.uk
Background Intensive care unit-acquired weakness (ICUAW) is a debilitating condition
associated with muscle wasting, that impacts clinical outcomes and costs of care. The aim of …
associated with muscle wasting, that impacts clinical outcomes and costs of care. The aim of …