New insights into the latest advancement in α-amylase inhibitors of plant origin with anti-diabetic effects
The rising predominance of type 2 diabetes, combined with the poor medical effects seen
with commercially available anti-diabetic medications, has motivated the development of …
with commercially available anti-diabetic medications, has motivated the development of …
[HTML][HTML] Anti-allergic and anti-inflammatory signaling mechanisms of natural compounds/extracts in in vitro system of RBL-2H3 cell: a systematic review
TS Rana, RR Bansode, LL Williams - Cells, 2024 - mdpi.com
Various extracts are tested for anti-allergic or anti-inflammatory properties on in vitro models.
RBL-2H3 cells are widely used in allergic or immunological studies. FCεRI and its …
RBL-2H3 cells are widely used in allergic or immunological studies. FCεRI and its …
Exploring synergistic inhibitory mechanisms of flavonoid mixtures on α-glucosidase by experimental analysis and molecular dynamics simulation
J Pan, M Nawaz, J Liu, H Liu, Z Lv, W Yang, Z Jiao… - Food Chemistry, 2025 - Elsevier
The study was the first to evaluate the synergistic interaction of luteolin+ quercetin, luteolin+
3-O-methylquercetin, and quercetin+ 3-O-methylquercetin mixtures on α-glucosidase and …
3-O-methylquercetin, and quercetin+ 3-O-methylquercetin mixtures on α-glucosidase and …
Enhancing the inhibitory activities of polyphenols in passion fruit peel on α-Amylase and α-Glucosidase via β-Glucosidase-producing Lactobacillus fermentation
F Tang, B Wei, C Qin, L Huang, N Xia, J Teng - Food Bioscience, 2024 - Elsevier
Passion fruit peel contained various phenolic compounds with α-glucosidase and α-amylase
inhibitory activities in vitro. However, the bound state and glycosylated forms hindered their …
inhibitory activities in vitro. However, the bound state and glycosylated forms hindered their …
Discovery of novel thiazole derivatives containing pyrazole scaffold as PPAR-γ Agonists, α-Glucosidase, α-Amylase and COX-2 inhibitors; Design, synthesis and in …
A novel series of thiazole derivatives with pyrazole scaffold 16a-l as hybrid rosiglitazone/
celecoxib analogs was designed, synthesized and tested for its PPAR-γ activation, α …
celecoxib analogs was designed, synthesized and tested for its PPAR-γ activation, α …
Integrative metabolomics and chemometrics depict the metabolic alterations of differently processed red kidney beans (Phaseolus vulgaris L.) and in relation to in-vitro …
DS Ghallab, DA Ghareeb, DA Goda - Food Research International, 2024 - Elsevier
Red kidney beans (RKB) serve as a powerhouse packed with a plethora of largely
unexplored extraordinary chemical entities with potential significance. However, their …
unexplored extraordinary chemical entities with potential significance. However, their …
[HTML][HTML] Structure-function relationships in (poly) phenol-enzyme binding: Direct inhibition of human salivary and pancreatic α-amylases
Abstract (Poly) phenols inhibit α-amylase by directly binding to the enzyme and/or by
forming starch-polyphenol complexes. Conventional methods using starch as the substrate …
forming starch-polyphenol complexes. Conventional methods using starch as the substrate …
Chemical, microbial, and functional characterization of a new fruity probiotic kombucha
TO Silva, GN Costa, M dos Santos Lima… - Food Research …, 2024 - Elsevier
This study aimed to evaluate the effect of adding Lacticaseibacillus casei as probiotic culture
and/or camu-camu (Myrciaria dubia) pulp on the chemical profile, technological, functional …
and/or camu-camu (Myrciaria dubia) pulp on the chemical profile, technological, functional …
Discovery of novel flavonoid derivatives as potential dual inhibitors against α-glucosidase and α-amylase: Virtual screening, synthesis, and biological evaluation
Diabetes mellitus is one of the top ten causes of death worldwide, accounting for 6.7 million
deaths in 2021, and is one of the most rapidly growing global health emergencies of this …
deaths in 2021, and is one of the most rapidly growing global health emergencies of this …
Dietary natural products as inhibitors of α-amylase and α-glucosidase: an updated review of ligand-receptor correlations validated by docking studies
M Rangel-Galván, Y Pacheco-Hernández… - Food Bioscience, 2024 - Elsevier
A therapeutic strategy to treat Type 2 diabetes mellitus (T2D) is focused on controlling
postprandial glucose levels by inhibiting α-amylase and α-glucosidase. These enzymes are …
postprandial glucose levels by inhibiting α-amylase and α-glucosidase. These enzymes are …