Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma: New Approved Options

AM García-Sancho, A Cabero… - Journal of Clinical …, 2023 - mdpi.com
Overall, around 40% of patients with diffuse large B-cell lymphoma (DLBCL) have refractory
disease or relapse after the first line of treatment. Until relatively recently, the prognosis of …

The future of immunotherapy for diffuse large B‐cell lymphoma

J Duell, J Westin - International Journal of Cancer, 2024 - Wiley Online Library
With the introduction of anti‐CD19 chimeric antigen receptor (CAR) T‐cell (CAR T)
therapies, bispecific CD3/CD20 antibodies and anti‐CD19 antibodies, immunotherapy …

Sequencing of anti-CD19 therapies in the management of diffuse large B-cell lymphoma

J Lownik, J Boiarsky, R Birhiray, A Merchant… - Clinical Cancer …, 2024 - AACR
Several second-and third-line immunotherapeutic options for patients with relapsed or
refractory diffuse large B-cell lymphoma ineligible for autologous stem cell transplant are …

Novel Targets and Advanced Therapies in Diffuse Large B Cell Lymphomas

F D'Alò, S Bellesi, E Maiolo, E Alma, F Bellisario… - Cancers, 2024 - mdpi.com
Simple Summary Diffuse large B cell lymphoma is the most common type of B cell
neoplasm, and can be cured by traditional chemoimmunotherapy in 60–70% of cases …

Tafasitamab for the treatment of patients with diffuse large B-cell lymphoma

MC Pirosa, A Stathis, E Zucca - 2024 - Taylor & Francis
Patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) require
additional treatments, especially those not eligible or not responding to high dose cytotoxic …

Time‐dependent cost comparison and health economic impact analysis of second‐line interventions for transplant‐ineligible patients with relapsed or refractory …

MS Kurte, AC Siefen, F Jakobs, T Poos… - European Journal of …, 2024 - Wiley Online Library
Objectives Novel interventions (axicabtagene ciloleucel [axi‐cel], lisocabtagene maraleucel
[liso‐cel], tafasitamab‐lenalidomide [Tafa‐L], polatuzumab‐rituximab‐bendamustine [pola …

A real-world pharmacovigilance study of tafasitamab: data mining of the US food and drug administration adverse event reporting system

Z Xu, S Feng, D Huang, H Wang, J Liu… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Background Tafasitamab is the first anti-CD19 monoclonal antibody approved for
relapsed/refractory diffuse large B-cell lymphoma patients ineligible for autologous stem cell …

[HTML][HTML] Utilization of Real-World Data to Facilitate Clinical Trials for Patients with Lymphoma

D Chihara, BP Hobbs, MJ Maurer, CR Flowers - Pharmacoepidemiology, 2024 - mdpi.com
The future directions in leveraging real-world evidence (RWE) and real-world data (RWD) in
the field of lymphoma, as compared to traditional experimental clinical trials, are poised to …

The current landscape of frontline large B cell lymphoma trials

D Qualls, P Armand, G Salles - Blood, 2024 - Elsevier
Abstract At least 25-35% of patients with large B cell lymphoma (LBCL) are not cured with
frontline treatment, with generally poor subsequent outcomes. This motivates ongoing and …

[HTML][HTML] 血液肿瘤精准诊治

张曦 - 2024 - aammt.tmmu.edu.cn
目的随着对血液肿瘤发病机制的深入研究, 血液肿瘤的精准诊断和分层治疗逐年优化提升.
近年来在人工智能的推动下, 血液肿瘤诊断由人工化, 经验化不断向智能化, 信息化升级 …