It has long been axiomatic that a protein's structure determines its function. Intrinsically
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …

Pestiviruses are among the economically most important pathogens of livestock. The biology
of these viruses is characterized by unique and interesting features that are both crucial for …

Dengue virus is responsible for the highest rates of disease and mortality among the
members of the Flavivirus genus. Dengue epidemics are still occurring around the world …

Pestiviruses are some of the most significant pathogens affecting ruminants and swine.
Here, we assembled a 11 276 bp contig encoding a predicted 3635 aa polyprotein from …

The existence and functioning of intrinsically disordered proteins (IDPs) challenge the
classical structure-function paradigm that equates function with a well-defined 3D structure …

Dengue virus affects hundreds of millions of people each year around the world, causing a
tremendous social and economic impact on affected countries. The aim of this review is to …

One of the core standards of biochemistry is that the function of a protein relies on its 3D
structure. This idea posits that all the information required for a protein to perform its …

Recently, Zika virus (ZIKV) emerged as a global public health concern and is distinct from
other flaviviruses in many aspects, for example, causing transplacental infection, fetal …

Abstract Dengue (DENV) and Zika (ZIKV) viruses are clinically important members of the
Flaviviridae family with an 11 kb positive strand RNA genome that folds to enable virus …

Dengue virus (DENV), which can lead to fatal hemorrhagic fever, affects 390 million people
worldwide. The closely related Zika virus (ZIKV) causes microcephaly in newborns and …