Psychedelics as medicines: an emerging new paradigm

DE Nichols, MW Johnson… - Clinical Pharmacology & …, 2017 - Wiley Online Library
Scientific interest in serotonergic psychedelics (eg, psilocybin and LSD; 5‐HT2A receptor
agonists) has dramatically increased within the last decade. Clinical studies administering …

Functional contribution of the medial prefrontal circuitry in major depressive disorder and stress-induced depressive-like behaviors

TP Bittar, B Labonté - Frontiers in behavioral neuroscience, 2021 - frontiersin.org
Despite decades of research on the neurobiology of major depressive disorder (MDD), the
mechanisms underlying its expression remain unknown. The medial prefrontal cortex …

Abnormal structural networks characterize major depressive disorder: a connectome analysis

MS Korgaonkar, A Fornito, LM Williams, SM Grieve - Biological psychiatry, 2014 - Elsevier
Background Major depressive disorder (MDD) has been shown to be associated with a
disrupted topological organization of functional brain networks. However, little is known …

Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study

CT Li, MH Chen, CH Juan, HH Huang, LF Chen… - Brain, 2014 - academic.oup.com
Theta-burst transcranial magnetic stimulation could modulate cortical excitability and has the
potential to treat refractory depression. However, there has been a lack of large randomized …

EEG alpha asymmetry as a gender-specific predictor of outcome to acute treatment with different antidepressant medications in the randomized iSPOT-D study

M Arns, G Bruder, U Hegerl, C Spooner… - Clinical …, 2016 - Elsevier
Objective To determine whether EEG occipital alpha and frontal alpha asymmetry (FAA)
distinguishes outpatients with major depression (MDD) from controls, predicts …

Chronic pain and psychedelics: a review and proposed mechanism of action

JP Castellanos, C Woolley, KA Bruno… - Regional Anesthesia & …, 2020 - rapm.bmj.com
The development of chronic pain is a complex mechanism that is still not fully understood.
Multiple somatic and visceral afferent pain signals, when experienced over time, cause a …

Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings

G Northoff, E Sibille - Molecular psychiatry, 2014 - nature.com
Major depression is a complex and severe psychiatric disorder whose symptomatology
encompasses a critical shift in awareness, especially in the balance from external to internal …

Sexually transmitted infection among adolescents and young adults with attention-deficit/hyperactivity disorder: a nationwide longitudinal study

MH Chen, JW Hsu, KL Huang, YM Bai, NY Ko… - Journal of the American …, 2018 - Elsevier
Objective Previous studies have suggested that attention-deficit/hyperactivity disorder
(ADHD) is related to risky sexual behaviors, which have been regarded as a major risk factor …

Optogenetic and chemogenetic insights into the neurocircuitry of depression‐like behaviour: A systematic review

T Biselli, SS Lange, L Sablottny… - European journal of …, 2021 - Wiley Online Library
Major depressive disorder (MDD) and its treatment are challenges for global health.
Optogenetics and chemogenetics are driving MDD research forward by unveiling causal …

Differentiating responders and non-responders to rTMS treatment for depression after one week using resting EEG connectivity measures

NW Bailey, KE Hoy, NC Rogasch, RH Thomson… - Journal of affective …, 2019 - Elsevier
Background Non-response to repetitive transcranial magnetic stimulation (rTMS) treatment
for depression is costly for both patients and clinics. Simple and cheap methods to predict …