Updates on cytogenetics and molecular genetics of bone and soft tissue tumors:: Ewing sarcoma and peripheral primitive neuroectodermal tumors

AA Sandberg, JA Bridge - Cancer genetics and cytogenetics, 2000 - Elsevier
Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

The Ewing family of tumors: Ewing's sarcoma and primitive neuroectodermal tumors

HE Grier - Pediatric Clinics of North America, 1997 - Elsevier
The Ewing family of tumors (Ewing's sarcoma and primitive neuroectodermal tumor [PNET])
is the second most common malignant bone tumor (after osteogenic sarcoma) in children …

Morphologic and immunophenotypic diversity in Ewing family tumors: a study of 66 genetically confirmed cases

AL Folpe, JR Goldblum, BP Rubin… - The American journal …, 2005 - journals.lww.com
More than 85% of Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET), or “Ewing
family of tumors”(EFTs), have the translocation, t (11; 22)(q24; q12), with others having …

Biology of EWS/ETS fusions in Ewing's family tumors

A Arvand, CT Denny - Oncogene, 2001 - nature.com
Tumor-associated chromosomal translocations lead to the formation of chimeric fusions
between the EWS gene and one of five different ETS transcription factors in Ewing's family …

Ewing's sarcoma: diagnostic, prognostic, and therapeutic implications of molecular abnormalities

SA Burchill - Journal of clinical pathology, 2003 - jcp.bmj.com
The identification of the non-random chromosome rearrangements between the EWS gene
on chromosome 22q12 and members of the ETS gene family in Ewing's sarcoma, peripheral …

Poorly differentiated synovial sarcoma: immunohistochemical distinction from primitive neuroectodermal tumors and high-grade malignant peripheral nerve sheath …

AL Folpe, RA Schmidt, D Chapman… - The American journal of …, 1998 - journals.lww.com
Synovial sarcoma is a relatively common sarcoma in adults, which in its classic bimorphic
form infrequently poses a diagnostic problem. Monomorphic spindled variants, as well as …

Primary malignant neuroepithelial tumors of the kidney: a clinicopathologic analysis of 146 adult and pediatric cases from the National Wilms' Tumor Study Group …

DM Parham, GJ Roloson, M Feely… - The American journal …, 2001 - journals.lww.com
Primary malignant neuroepithelial tumors of the kidney (NETKs) comprise a group of
primitive, highly malignant neoplasms that histologically and clinically are not well …

EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors

S Hu-Lieskovan, J Zhang, L Wu, H Shimada… - Cancer research, 2005 - AACR
Tumor-specific translocations are common in tumors of mesenchymal origin. Whether the
translocation determines the phenotype, or vice versa, is debatable. Ewing's family tumors …

Soft tissue tumors associated with EWSR1 translocation

S Romeo, AP Dei Tos - Virchows Archiv, 2010 - Springer
The Ewing sarcoma breakpoint region 1 (EWSR1; also known as EWS) represents one of
the most commonly involved genes in sarcoma translocations. In fact, it is involved in a …

Ewing sarcoma family of tumors

AV Maheshwari, EY Cheng - … -Journal of the American Academy of …, 2010 - journals.lww.com
The Ewing sarcoma family of tumors (ESFT) consists of a group of tumors characterized by
morphologically similar round-cell neoplasm and by the presence of a common …