Recent progress in solid‐state nanopores

K Lee, KB Park, HJ Kim, JS Yu, H Chae… - Advanced …, 2018 - Wiley Online Library
The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …

Emerging tools for studying single entity electrochemistry

Y Wang, X Shan, N Tao - Faraday discussions, 2016 - pubs.rsc.org
Electrochemistry studies charge transfer and related processes at various microscopic
structures (atomic steps, islands, pits and kinks on electrodes), and mesoscopic materials …

Non-equilibrium molecular dynamics simulation to evaluate the effect of confinement on fluid flow in silica nanopores

P Asai, J Jin, M Deo, JD Miller, D Butt - Fuel, 2022 - Elsevier
The flow of fluids in nano-confinement has applications in separations, water purification,
medical systems and in the recovery of fluids in petroleum systems. It is believed that fluids …

Protein transport through nanopores illuminated by long-time-scale simulations

G Mitscha-Baude, B Stadlbauer, S Howorka… - ACS …, 2021 - ACS Publications
The transport of molecules through nanoscale confined space is relevant in biology,
biosensing, and industrial filtration. Microscopically modeling transport through nanopores is …

Real-time structural signatures of protein allostery by electrically-and mechanically-coupled sensing

M Zhang, Z Zheng, J Zhou, Q Ding, M Long, S Lü - Nano Today, 2024 - Elsevier
Accurate detection and identification of conformational evolutions are essential to describe
the micro-structural mechanisms of protein allostery. Here we establish an approach by …

Nonequilibrium capture rates induce protein accumulation and enhanced adsorption to solid-state nanopores

KJ Freedman, SR Haq, MR Fletcher, JP Foley… - ACS …, 2014 - ACS Publications
Single molecule capturing of analytes using an electrically biased nanopore is the
fundamental mechanism in which nearly all nanopore experiments are conducted. With pore …

Ionic flow through partially blocked nanopores

S Mohapatra, H Teherpuria, S Mogurampelly… - Physical Chemistry …, 2024 - pubs.rsc.org
Employing atomistic molecular dynamics simulations, we investigate the ionic conductivity
mechanisms in a partially blocked nanopore containing a centrally positioned spherical …

Mapping shifts in nanopore signal to changes in protein and protein‐DNA conformation

A Carlsen, V Tabard‐Cossa - Proteomics, 2022 - Wiley Online Library
Solid‐state nanopores have been used extensively in biomolecular studies involving DNA
and proteins. However, the interpretation of signals generated by the translocation of …

Label-free screening of single biomolecules through resistive pulse sensing technology for precision medicine applications

S Harrer, SC Kim, C Schieber, S Kannam… - …, 2015 - iopscience.iop.org
Employing integrated nano-and microfluidic circuits for detecting and characterizing
biological compounds through resistive pulse sensing technology is a vibrant area of …

Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores

M Zhang, S Chen, J Hu, Q Ding, L Li, S Lü, M Long - Nanoscale, 2021 - pubs.rsc.org
Conformational changes of proteins play a vital role in implementing their functions and
revealing the underlying mechanisms in various biological processes. It is still challenging to …