Event-based control of autonomic and emotional states by the anterior cingulate cortex

JK Seamans, SB Floresco - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Despite being an intensive area of research, the function of the anterior cingulate cortex
(ACC) remains somewhat of a mystery. Human imaging studies implicate the ACC in various …

Mistakes were made: neural mechanisms for the adaptive control of action initiation by the medial prefrontal cortex

M Laubach, MS Caetano, NS Narayanan - Journal of Physiology-Paris, 2015 - Elsevier
Studies in rats, monkeys and humans have established that the medial prefrontal cortex is
crucial for the ability to exert adaptive control over behavior. Here, we review studies on the …

Cell-type-specific activity in prefrontal cortex during goal-directed behavior

L Pinto, Y Dan - Neuron, 2015 - cell.com
The prefrontal cortex (PFC) plays a key role in controlling goal-directed behavior. Although a
variety of task-related signals have been observed in the PFC, whether they are differentially …

[HTML][HTML] Brain-wide neural activity underlying memory-guided movement

S Chen, Y Liu, ZA Wang, J Colonell, LD Liu, H Hou… - Cell, 2024 - cell.com
Behavior relies on activity in structured neural circuits that are distributed across the brain,
but most experiments probe neurons in a single area at a time. Using multiple Neuropixels …

Dynamics of multistable states during ongoing and evoked cortical activity

L Mazzucato, A Fontanini… - Journal of Neuroscience, 2015 - Soc Neuroscience
Single-trial analyses of ensemble activity in alert animals demonstrate that cortical circuits
dynamics evolve through temporal sequences of metastable states. Metastability has been …

Stimuli reduce the dimensionality of cortical activity

L Mazzucato, A Fontanini, G La Camera - Frontiers in systems …, 2016 - frontiersin.org
The activity of ensembles of simultaneously recorded neurons can be represented as a set
of points in the space of firing rates. Even though the dimension of this space is equal to the …

A hippocampus to prefrontal cortex neural pathway inhibits food motivation through glucagon-like peptide-1 signaling

TM Hsu, EE Noble, CM Liu, AM Cortella… - Molecular …, 2018 - nature.com
The hippocampus and the medial prefrontal cortex (mPFC) are traditionally associated with
regulating memory and executive function, respectively. The contribution of these brain …

Behavioral state-dependent modulation of prefrontal cortex activity by respiration

S Folschweiller, JF Sauer - Journal of Neuroscience, 2023 - Soc Neuroscience
Respiration-rhythmic oscillations in the local field potential emerge in the mPFC, a cortical
region with a key role in the regulation of cognitive and emotional behavior. Respiration …

Expectation-induced modulation of metastable activity underlies faster coding of sensory stimuli

L Mazzucato, G La Camera, A Fontanini - Nature neuroscience, 2019 - nature.com
Sensory stimuli can be recognized more rapidly when they are expected. This phenomenon
depends on expectation affecting the cortical processing of sensory information. However …

Hunger or thirst state uncertainty is resolved by outcome evaluation in medial prefrontal cortex to guide decision-making

AK Eiselt, S Chen, J Chen, J Arnold, T Kim… - Nature …, 2021 - nature.com
Physiological need states direct decision-making toward re-establishing homeostasis. Using
a two-alternative forced choice task for mice that models elements of human decisions, we …