A key challenge of modern biology is to uncover the functional role of the protein entities that
compose cellular proteomes. To this end, the availability of reliable three-dimensional …

Despite recent efforts to develop automated protein structure determination protocols,
structural genomics projects are slow in generating fold assignments for complete …

This work presents RaptorX, a statistical method for template‐based protein modeling that
improves alignment accuracy by exploiting structural information in a single or multiple …

Motivation: Consensus structure prediction methods (meta-predictors) have higher accuracy
than individual structure prediction algorithms (their components). The goal for the …

Background A comprehensive update of the classification of all available kinases was
carried out. This survey presents a complete global picture of this large functional class of …

This article studies the protein side-chain packing problem using the tree-decomposition of a
protein structure. To obtain fast and accurate protein side-chain packing, protein structures …

Protein threading is one of the most successful protein structure prediction methods. Most
protein threading methods use a scoring function linearly combining sequence and structure …

We present the results of the fully automated CAFASP3 experiment, which was carried out in
parallel with CASP5, using the same set of prediction targets. CAFASP participation is …

This paper proposes a novel tree decomposition based side-chain assignment algorithm,
which can obtain the globally optimal solution of the side-chain packing problem very …

This paper proposes a tree decomposition of protein structures, which can be used to
efficiently solve two key subproblems of protein structure prediction: protein threading for …