HIC-Vac is an international network of researchers dedicated to developing human infection
challenge studies to accelerate vaccine development against pathogens of high global …

Background Pharyngeal colonisation by the commensal bacterium Neisseria lactamica
inhibits colonisation by Neisseria meningitidis and has an inverse epidemiological …

Background: Pregnant women have historically been excluded from most medical research,
including human challenge studies. The proof-of-concept Lactamica 9 human challenge …

Introduction Infant upper respiratory microbiota are derived partly from the maternal
respiratory tract, and certain microbiota are associated with altered risk of infections and …

The infant respiratory microbiome is derived largely from its mother and is associated with 3
downstream health and disease. Manipulating maternal respiratory flora peripartum to 4 …

Meningococcal disease is a globally important cause of mortality and morbidity, particularly
in the meningitis belt of Sub-Saharan Africa. The causative agent, Neisseria meningitidis …

Moraxella catarrhalis is a pathogen of increasing importance and is recognised as one of
the most common causes of respiratory tract infection. In particular, it is known for its role in …

Background: The Gram staining procedure, a fundamental microbiological technique
established in 1884, is crucial for bacterial identification and classification. Despite its …