Mode of action of astrocytes in pain: From the spinal cord to the brain

Y Chen, X Feng, CW Cheung, JA Liu - Progress in Neurobiology, 2022 - Elsevier
Chronic pain is a maladaptive condition affecting 7%− 10% of the population worldwide and
can be accompanied by depression, anxiety, and insomnia. In particular, chronic pain is …

Brain stimulation for chronic pain management: a narrative review of analgesic mechanisms and clinical evidence

M Szymoniuk, JH Chin, Ł Domagalski, M Biszewski… - Neurosurgical …, 2023 - Springer
Chronic pain constitutes one of the most common chronic complaints that people
experience. According to the International Association for the Study of Pain, chronic pain is …

[HTML][HTML] Insular cortex stimulation alleviates neuropathic pain through changes in the expression of collapsin response mediator protein 2 involved in synaptic …

K Kim, G Nan, H Bak, HY Kim, J Kim, M Cha… - Neurobiology of …, 2024 - Elsevier
In recent studies, brain stimulation has shown promising potential to alleviate chronic pain.
Although studies have shown that stimulation of pain-related brain regions can induce pain …

Mutual interaction between motor cortex activation and pain in fibromyalgia: EEG-fNIRS study

E Gentile, A Brunetti, K Ricci, M Delussi, V Bevilacqua… - PLoS …, 2020 - journals.plos.org
Background Experimental and clinical studies suggested an analgesic effect on chronic pain
by motor cortex activation. The present study explored the complex mechanisms of …

Suppression of neuropathic pain and comorbidities by recurrent cycles of repetitive transcranial direct current motor cortex stimulation in mice

Z Gan, H Li, PV Naser, MJ Oswald, R Kuner - Scientific Reports, 2021 - nature.com
Transcranial, minimally-invasive stimulation of the primary motor cortex (M1) has recently
emerged to show promise in treating clinically refractory neuropathic pain. However, there is …

The effectiveness of home-based transcranial direct current stimulation on chronic pain: A systematic review and meta-analysis

A Antonioni, A Baroni, G Fregna, I Ahmed… - Digital …, 2024 - journals.sagepub.com
Objective As highlighted by the COVID-19 pandemic, identifying strategies for home-based
patient management is crucial. As pain is highly prevalent and imposes significant burdens …

Automatic microscopic detection of mycobacteria in sputum: a proof-of-concept

D Zingue, P Weber, F Soltani, D Raoult… - Scientific Reports, 2018 - nature.com
The laboratory diagnosis of lung mycobacterioses including tuberculosis comprises the
microscopic examination of sputum smear after appropriate staining such as Ziehl-Neelsen …

Recent advances in pain management: relevant protein kinases and their inhibitors

F Giraud, E Pereira, F Anizon, P Moreau - Molecules, 2021 - mdpi.com
The purpose of this review is to underline the protein kinases that have been established,
either in fundamental approach or clinical trials, as potential biological targets in pain …

Microarray analyses of lncRNAs and mRNAs expression profiling associated with diabetic peripheral neuropathy in rats

G Guo, S Ren, Y Kang, Y Liu, D Duscher… - Journal of cellular …, 2019 - Wiley Online Library
Diabetic peripheral neuropathy (DPN) is considered to be the most frequent neuropathic
complication of diabetes, and severely affects the quality of life of patients. Long noncoding …

[HTML][HTML] Effects of mTOR inhibitors on neuropathic pain revealed by optical imaging of the insular cortex in rats

K Kim, S Choi, M Cha, BH Lee - Brain research, 2020 - Elsevier
In the pain matrix, the insular cortex (IC) is mainly involved in discriminative sensory and
motivative emotion. Abnormal signal transmission from injury site causes neuropathic pain …