Solute carriers of the glucose transporter (GLUT) family mediate the first step for cellular
glucose usage. The upregulation of GLUT s has been reported in numerous cancer types as …

A common set of functional characteristics of cancer cells is that cancer cells consume a
large amount of glucose, maintain high rate of glycolysis and convert a majority of glucose …

Background Apoptosis and other forms of cell death have been intensively investigated in
the past years to explain the mode of action of synthetic anticancer drugs and natural …

Trastuzumab shows remarkable efficacy in treatment of ErbB2-positive breast cancers when
used alone or in combination with other chemotherapeutics. However, acquired resistance …

Reprogramming of cellular energy metabolism is widely accepted to be a cancer hallmark.
The deviant energetic metabolism of cancer cells-known as the Warburg effect-consists in …

Accelerated glycolysis is one of the biochemical characteristics of cancer cells. The glucose
transporter isoform 1 (GLUT1) gene encodes a key rate-limiting factor in glucose transport …

Glucose and other carbohydrates are transported into cells using members of a family of
integral membrane glucose transporter (GLUT) molecules. To date 14 members of this …

Aim: A novel biomimetic strategy was employed for presenting antibodies on gold nanorods
(NRs) to target growth factor receptors on cancer cells for use in photothermal therapy …

Background Apigenin is one of the most abundant dietary flavonoids that possesses multiple
bio-functions. Purpose This study was designed to determine the influence of apigenin on …

Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …