Pyrroloquinolines, imidazoquinolines, and pyrroloquinazolines with a bridgehead nitrogen

F Dumitrascu, F Georgescu, E Georgescu… - Advances in Heterocyclic …, 2019 - Elsevier
This chapter presents recent advances in the chemistry of heterocyclic ring systems with a
nitrogen bridgehead including pyrrolo [1, 2-a] quinoline, imidazo [1, 2-a] quinoline, imidazo …

Pharmacokinetics, pharmacodynamics and safety profiling of IS01957, a preclinical candidate possessing dual activity against inflammation and nociception

A Sharma, A Magotra, A Dogra, SK Rath… - Regulatory Toxicology …, 2017 - Elsevier
In spite of unprecedented advances in modern systems of medicine, there is necessity for
exploration of traditional plant based secondary metabolites or their semisynthetic …

Exploring Derivatives of Quinazoline Alkaloid l-Vasicine as Cap Groups in the Design and Biological Mechanistic Evaluation of Novel Antitumor Histone Deacetylase …

M Ahmad, MA Aga, JA Bhat, B Kumar… - Journal of medicinal …, 2017 - ACS Publications
l-Vasicine is a quinazoline alkaloid with an electron dense ring and additional functionalities
in its structure. Employing target oriented synthesis (TOS) based on in silico studies …

Fluorocyclization of Vinyl Azides for the Formation of 3‐Azido Heterocycles

D Bai, L Li, X Li, Y Lu, Y Wu… - Chemistry–An Asian …, 2020 - Wiley Online Library
Azido saturated heterocycles are important for therapeutic‐development but challenging to
prepare. Disclosed herein is a novel synthetic strategy for 3‐azido heterocycles via …

Síntese de amidas e amidas-graxas utilizando metodologias aplicadas ao princípios da química verde

RN Lima - 2018 - teses.usp.br
Várias são as metodologias disponíveis para a síntese de amidas, entretanto a motivação
hoje em dia é desenvolver métodos sustentáveis que reduzam os desperdícios e custos dos …