Sustainable approaches for the study of alkaloids from plants using supercritical fluid-based processes

J Pavón-Pérez, A Vallejos-Almirall, C Agurto-Muñoz… - Green …, 2022 - pubs.rsc.org
Plant alkaloids are natural secondary metabolites that have attracted great interest in the
development of drugs for therapeutic applications due to their diverse bioactivities. For the …

LC-MS Analysis, Computational Investigation, and Antimalarial Studies of Azadirachta indica Fruit

KO Faloye, SA Adesida… - … and Biology Insights, 2023 - journals.sagepub.com
Malaria is a deadly disease that continues to pose a threat to children and maternal well-
being. This study was designed to identify the chemical constituents in the ethanolic fruit …

Investigating the multitargeted anti-diabetic potential of cucurbitane-type triterpenoid from Momordica charantia: an LC-MS, docking-based MM\GBSA and MD …

SO Famuyiwa, S Ahmad, KO Olufolabo… - Journal of …, 2023 - Taylor & Francis
Type 2 diabetes accounts for the largest percentage of all diabetic cases worldwide.
Cucurbitane-type triterpenes are mainly found in Momordica charantia and possess …

Antimalarial potential, LC–MS secondary metabolite profiling and computational studies of Zingiber officinale

KO Faloye, MK Tripathi, SA Adesida… - Journal of …, 2024 - Taylor & Francis
Malaria is among the top-ranked parasitic diseases that pose a threat to the existence of the
human race. This study evaluated the antimalarial effect of the rhizome of Zingiber officinale …

Plasmepsin II inhibitory potential of phytochemicals isolated from African antimalarial plants: a computational approach

KO Faloye, MK Tripathi, EG Fakola… - Journal of …, 2023 - Taylor & Francis
Plamepsin II has been identified as a therapeutic target in the Plasmodium falciparum's life
cycle and may lead to a drastic reduction in deaths caused by malaria worldwide. Africa flora …

Antimalarial Studies and Phytochemical Profiling of Laportea aestuans (L.) Chew Extractives

KO Faloye, SA Oguntimehin… - Natural Product …, 2024 - journals.sagepub.com
Background and objectives This study validated the antimalarial efficacy of Laportea
aestuans extract using chemosuppressive and curative models, identified its most active …

Secondary metabolites from the stem bark of Alstonia boonei and the seeds of Picralima nitida with antibacterial activities

AO Adepiti, DK Nyamboki, GB Kibrom… - Natural Product …, 2024 - Taylor & Francis
The methanol stem bark extract of A. boonei and methanol seed extract of P. nitida, were
subjected to purification using chromatographic techniques. A. boonei yielded loganic acid …